Seroprevalence of Anti-SARS-CoV-2 IgG Antibody in Healthcare Workers: A Report From Rafsanjan City

M. Tashakori, A. Jamalizadeh, M. Nejad-Ghaderi, M. Hadavi, Aliakbar Yousefi-Ahmadipour, Fateme Mohseni Moghadam, Athareh Soresrafil, Kazem Mashayekhi
{"title":"Seroprevalence of Anti-SARS-CoV-2 IgG Antibody in Healthcare Workers: A Report From Rafsanjan City","authors":"M. Tashakori, A. Jamalizadeh, M. Nejad-Ghaderi, M. Hadavi, Aliakbar Yousefi-Ahmadipour, Fateme Mohseni Moghadam, Athareh Soresrafil, Kazem Mashayekhi","doi":"10.32598/jid.25.4.4","DOIUrl":null,"url":null,"abstract":"Background: Healthcare workers (HCWs) have a high risk of catching SARS-CoV-2 infection. Seroprevalence studies can provide related data on HCWs with a history of infections. Despite numerous seroepidemiological reports of COVID-19 in different groups, there are no such reports for HCWs working in Rafsanjan City, Iran. This study aimed to determine the SARS-CoV-2 seroprevalence among HCWs. Methods: Blood samples were obtained from 295 participants, including healthcare personnel and administrative staff. The SARS-CoV-2 IgG antibody was measured by the ELISA method, and the obtained data were analyzed with the Chi-square test and logistic regression. A P<0.05 was considered statistically significant. Results: The previous exposure to COVID-19 was higher in HCWs than in administrative department staff. Fifteen out of 130 (11.5%) participants had experienced SARS-CoV-2 infection without any symptoms. The results of logistic regression indicated that traveling (OR: 018, 95% CI: 0.08–0.74, P=0.001), occupation (OR: 0.2, 95% CI: 0.01–0.94, P<0.05), history of respiratory problems (OR: 0.15, 95% CI: 0.01–1.94, P<0.05), and major clinical signs (OR: 8.09, 95% CI: 3.7-17.66, P<0.001) are important factors which affect SARS-CoV-2 IgG antibodies. Conclusion: Our results indicated an occupational risk for SARS-CoV-2 infection among HCWs. Because some HCWs are asymptomatic, their communication, such as traveling, must be controlled, and it is necessary to ensure the safety of HCWs and reduce their transfer to the community and patients.","PeriodicalId":91544,"journal":{"name":"Journal of inflammatory bowel diseases & disorders","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of inflammatory bowel diseases & disorders","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32598/jid.25.4.4","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Healthcare workers (HCWs) have a high risk of catching SARS-CoV-2 infection. Seroprevalence studies can provide related data on HCWs with a history of infections. Despite numerous seroepidemiological reports of COVID-19 in different groups, there are no such reports for HCWs working in Rafsanjan City, Iran. This study aimed to determine the SARS-CoV-2 seroprevalence among HCWs. Methods: Blood samples were obtained from 295 participants, including healthcare personnel and administrative staff. The SARS-CoV-2 IgG antibody was measured by the ELISA method, and the obtained data were analyzed with the Chi-square test and logistic regression. A P<0.05 was considered statistically significant. Results: The previous exposure to COVID-19 was higher in HCWs than in administrative department staff. Fifteen out of 130 (11.5%) participants had experienced SARS-CoV-2 infection without any symptoms. The results of logistic regression indicated that traveling (OR: 018, 95% CI: 0.08–0.74, P=0.001), occupation (OR: 0.2, 95% CI: 0.01–0.94, P<0.05), history of respiratory problems (OR: 0.15, 95% CI: 0.01–1.94, P<0.05), and major clinical signs (OR: 8.09, 95% CI: 3.7-17.66, P<0.001) are important factors which affect SARS-CoV-2 IgG antibodies. Conclusion: Our results indicated an occupational risk for SARS-CoV-2 infection among HCWs. Because some HCWs are asymptomatic, their communication, such as traveling, must be controlled, and it is necessary to ensure the safety of HCWs and reduce their transfer to the community and patients.
拉夫桑詹市卫生工作者抗sars - cov -2 IgG抗体血清阳性率报告
背景:卫生保健工作者是感染SARS-CoV-2的高危人群。血清患病率研究可为有感染史的卫生保健工作者提供相关数据。尽管在不同人群中有许多COVID-19血清流行病学报告,但在伊朗拉夫桑詹市工作的卫生保健工作者没有此类报告。本研究旨在确定医护人员中SARS-CoV-2的血清阳性率。方法:对295名医务人员和行政人员进行血样采集。采用ELISA法检测SARS-CoV-2 IgG抗体,所得数据采用卡方检验和logistic回归分析。P<0.05为差异有统计学意义。结果:卫生保健工作者的既往接触率高于行政部门工作人员。130名参与者中有15名(11.5%)经历了SARS-CoV-2感染,但没有任何症状。logistic回归结果显示,旅行(OR: 018, 95% CI: 0.08 ~ 0.74, P=0.001)、职业(OR: 0.2, 95% CI: 0.01 ~ 0.94, P<0.05)、呼吸系统病史(OR: 0.15, 95% CI: 0.01 ~ 1.94, P<0.05)、主要临床症状(OR: 8.09, 95% CI: 3.7 ~ 17.66, P<0.001)是影响SARS-CoV-2 IgG抗体的重要因素。结论:卫生保健工作者存在感染SARS-CoV-2的职业风险。由于部分医护人员无症状,必须控制其出行等交流,确保医护人员安全,减少向社区和患者转移。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信