Nonlinear Genetics Inbreeding and Genetic Load

Volobuev Andrey Nikolaevich, Romanchuk Peter Ivanovich, Malishev Vladimir Kirikovich
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引用次数: 2

Abstract

Comparison of concepts of occurrence and accumulation of the genetic load in result of inbreeding for a family tree and a population is given. It is shown that for the population the analysis of the genetic load concerns to area of nonlinear genetics. The nonlinear differential equation of the second order being the special case of the Hardy-Weinberg law at presence inbreeding for the population is found. The numerical decision of this equation allowed to find the law of increase of recessive allele frequency in the population is given. Some aspects of the traditional theory of the genetic load are considered.
非线性遗传、近交与遗传负荷
比较了家族树和群体近亲繁殖引起的遗传负荷的发生和积累的概念。结果表明,对群体的遗传负荷分析涉及非线性遗传领域。研究了群体近交时Hardy-Weinberg定律的二阶非线性微分方程。给出了该方程的数值求解方法,从而找到了群体中隐性等位基因频率增加的规律。考虑了遗传负荷传统理论的一些方面。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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