Main directions of research and achievements of the Laboratory of ecological physiology and product quality in 2000–2020

I. Kovalchuk, R. Fedoruk, M. Tsap
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Abstract

The article presents the main directions of research and the most significant results of the laboratory of ecological physiology and product quality of the Institute of Animal Biology of NAAS for twenty years of its activity. The results of basic research and applied developments obtained during the implementation of tasks included in the scientific programs of NAAS and the Scientific and Methodological Center “Animal Physiology” are presented. The main characteristics of the physiological impact of new effective feed additives and BAS, tested in production and implemented on different species of animals — cattle, sheep, poultry, rabbits, bees, in pond fish, substantiated methods of their use. The relationship between the degree of man-made pollution and the intensity of physiological and biochemical processes in animals, their adaptive and reproductive capacity. The method of arterio-venous difference in the mammary gland revealed some mechanisms of physiological influence of Cd in the body of cows during lactation under conditions of experimental loading of its salts of different concentrations, the level of biotransformation into milk. The study of the biological action of new organic compounds Se in cows, calves and breeding bulls was started for the first time. The composition of the feed additive based on the drug “Sel-Pleks” was developed and tested, which increases the immunobiological, productive and reproductive ability of the body of cows in the conditions of intensive technogenic load. New scientific data on the biological action of the developed protein-mineral supplements in the body of rabbits with different methods of maintenance and feeding. Physiological and biochemical mechanisms of influence of terms of weaning of young rabbits on immunobiological reactivity of an organism are found out. A recipe for granular feed with high protein content has been developed and its effect on growth intensity and physiological and biochemical processes in rabbits has been studied. Possibilities of application of genetically modified feeds in animal feeding and their influence on physiological status, ecological safety and quality of production are substantiated. The influence of GMO soybeans and products of their processing on the formation of adaptive reactions and functioning of individual organs and systems in animals has been studied. The absence of a pronounced negative effect of transgenic soy on the growth and development of the organism and its reproductive ability in female animals has been proved. The effect of Ge in the form of germanium citrate, obtained by nanotechnological method and chemically synthesized, on the state of the immune, reproductive antioxidant and detoxification systems of the body in laboratory rats of two generations has been studied. The peculiarities of ontogenetic development of male F1 rats under the action of different doses of germanium citrate have been elucidated. The possibility of using small and medium doses of germanium citrate to stimulate the body’s immune and antioxidant systems, its reproductive capacity in females of multiple animals is substantiated. Changes in physiological and biochemical parameters of blood and detoxification ability of rats F0 and F1 under the action of different doses of germanium citrate were established. The effect of different doses of germanium citrate on the content of biotic mineral elements in tissues and organs of animals has been studied. Peculiarities of histological structure of tissues of immunocompetent organs of female F1 rats under the action of different doses of germanium citrate are noted. The role of the laboratory staff in the improvement of existing and development of new methods of physiological, biochemical and ecological research, State standards, the possibility of their adaptation and harmonization to modern conditions of science and production is shown.
2000-2020年生态生理与产品质量实验室主要研究方向及成果
本文介绍了中国科学院动物生物学研究所生态生理与产品质量研究室成立20年来的主要研究方向和取得的重要成果。本文介绍了中国科学院和科学与方法中心“动物生理学”科学计划任务实施过程中取得的基础研究和应用开发成果。新的有效饲料添加剂和BAS的生理影响的主要特征,在生产中进行了测试,并在不同物种的动物-牛,羊,家禽,兔子,蜜蜂,池塘鱼中实施,证实了它们的使用方法。人为污染程度与动物生理生化过程强度及其适应和繁殖能力之间的关系。乳腺动静脉差异法揭示了不同浓度镉盐实验负荷、不同生物转化成乳水平下镉对奶牛泌乳期生理影响的一些机制。首次开展了新型有机化合物硒在奶牛、犊牛和种公牛体内的生物作用研究。研制并试验了以药物“self - pleks”为基础的饲料添加剂的组成,该添加剂可在密集的技术负荷条件下提高奶牛机体的免疫生物学、生产能力和繁殖能力。开发的蛋白质-矿物质补充剂在不同维持和饲养方法的家兔体内的生物作用的新的科学数据。探讨了幼兔断奶条件对机体免疫生物反应性影响的生理生化机制。研制了一种高蛋白颗粒饲料配方,并研究了其对家兔生长强度和生理生化过程的影响。证实了转基因饲料在动物饲养中应用的可能性及其对动物生理状态、生态安全和生产质量的影响。研究了转基因大豆及其加工产品对动物个体器官和系统的适应性反应形成和功能的影响。转基因大豆对生物的生长发育和雌性动物的生殖能力没有明显的负面影响。本文研究了纳米技术和化学合成的柠檬酸锗对两代实验大鼠机体免疫、生殖抗氧化和解毒系统状态的影响。研究了不同剂量枸橼酸锗作用下雄性F1大鼠个体发育的特点。应用中、小剂量枸橼酸锗刺激机体免疫和抗氧化系统的可能性得到了证实,其在多只雌性动物中的繁殖能力得到了证实。研究了不同剂量枸橼酸锗作用下大鼠F0和F1血液生理生化指标及解毒能力的变化。本文研究了不同剂量枸橼酸锗对动物组织器官中生物矿质元素含量的影响。观察了不同剂量枸橼酸锗作用下雌性F1大鼠免疫功能器官组织的组织学结构特点。展示了实验室工作人员在改进现有的和发展新的生理、生化和生态研究方法、国家标准方面的作用,以及它们适应和协调现代科学和生产条件的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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