Glioma and Extracellular Matrix, A Review on the Integrins as the Receptors of the Extracellular Matrix

Abstract

The brain extracellular matrix is a complex structure. The invading tumors like gliomas would interact with the extracellular matrix. There are receptors in the extracellular matrix including Integrins. This brief review tries to point to some important notes about the extracellular matrix and Integrins as a group of receptors in the extracellular matrix which can play the important role in the pathogenesis of gliomas in the brain tissue