Metabolic inhibitors as stimulating factors for citric acid production

Z. Nehad, M. Essam, A. Hába
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引用次数: 4

Abstract

The effect of some metabolic inhibitors on citric acid production by Aspergillus niger in cane molasses medium was investigated. Addition of 0.01-0.1 iodoacetic acid and sodium arsenate, 0.05 -1.0 sodium malonate, 0.01 sodium azide , 0.01-0.05 sodium fluoride , 0.1-1.0 EDTA stimulated citric acid production (5-49%), but not necessary total titratable acids. Higher concentrations 10mM of iodoacetic acid , sodium malonate and 0.5 mM sodium azide caused a complete inhibition of fungal growth. 0.2 mM of iodoacetic acid, sodium arsenate and sodium fluoride caused a remarkable inhibition of citric acid production. The implications of those preliminary functions was discussed.
代谢抑制剂作为柠檬酸生成的刺激因子
研究了几种代谢抑制剂对黑曲霉在甘蔗糖蜜培养基中产柠檬酸的影响。添加0.01-0.1的碘乙酸和砷酸钠、0.05 -1.0的丙二酸钠、0.01的叠氮化钠、0.01-0.05的氟化钠、0.1-1.0的EDTA可以刺激柠檬酸的产量(5-49%),但不需要总可滴定酸。较高浓度的碘乙酸、丙二酸钠和叠氮化钠分别为10mM和0.5 mM,对真菌生长有完全抑制作用。0.2 mM的碘乙酸、砷酸钠和氟化钠对柠檬酸的生成有显著的抑制作用。讨论了这些初步职能所涉问题。
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