{"title":"The study of the effect of the low molecular analog of neuropeptide Y on behavioral reactions in rats","authors":"A. Zagayko, I. Havrylov, D. Lytkin","doi":"10.24959/cphj.19.1509","DOIUrl":null,"url":null,"abstract":"“elevated plus-maze”. Results. Experiments in rats showed the presence of anxiolytic properties of the compound without the associated sedative effect. In the tests “open field” and “elevated plus-maze”, the activating effect of the compound on the locomo-tor activity and a decrease in vegetative manifestations were observed. Conclusions. The data obtained indicate that the neuropeptide Y modified fragment is able to affect the anxiety level and research activity of rats; it substantiates the feasibility of further studies of this experimental compound.","PeriodicalId":10498,"journal":{"name":"Clinical pharmacy","volume":"17 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical pharmacy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24959/cphj.19.1509","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
Abstract
“elevated plus-maze”. Results. Experiments in rats showed the presence of anxiolytic properties of the compound without the associated sedative effect. In the tests “open field” and “elevated plus-maze”, the activating effect of the compound on the locomo-tor activity and a decrease in vegetative manifestations were observed. Conclusions. The data obtained indicate that the neuropeptide Y modified fragment is able to affect the anxiety level and research activity of rats; it substantiates the feasibility of further studies of this experimental compound.