Development of Diagnostic and Therapeutic Strategy for Long QT Syndrome Using Human Induced Pluripotent Stem Cell Models

Daisuke Yoshinaga, T. Makiyama, Shiro Baba
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Abstract

of patient-specific iPSC-CMs. This method may also be useful in diagnosing cases where pathogenic genetic mutations cannot be identified. In addition, iPSC-CMs are being studied as an experimental model for the development of therapies for hereditary arrhythmias. Here, we discuss the latest iPSC technologies related to hereditary arrhythmias.
利用人诱导多能干细胞模型开发长QT综合征的诊断和治疗策略
患者特异性iPSC-CMs这种方法也可用于诊断致病性基因突变无法确定的病例。此外,iPSC-CMs正在作为遗传性心律失常治疗开发的实验模型进行研究。在此,我们讨论与遗传性心律失常相关的iPSC最新技术。
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