Prevalence estimation of diabetes mellitus among tuberculosis cases, its risk factors, and treatment outcome in Rajkot city

Pooja Ranpariya, H. Solanki, Rajesh K. Chudasama
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Abstract

Background: Tuberculosis (TB) and diabetes mellitus (DM) are the world’s leading public health issues. TB with DM co-morbidity adversely affects prognosis of individual diseases and its treatment outcome. Materials and Methods: A cross-sectional study was conducted at five TB units of Rajkot city for five quarters. Newly registered pulmonary TB (PTB) patients having DM during the study period were included as cases. All cases were followed up at the end of treatment to observe outcomes. Information was collected in a pretested proforma using the interview technique. Results: The prevalence of DM among PTB cases was 5%. Maximum cases were in 51–60 years (34.4%), male: female ratio was 3:1, living in urban slum (53.1%), literate (81.2%), and from middle socio-economic class (65.6%). One-fourth of the cases had family (28.1%) and past history (28.1%) of TB, and more than one-third (37.5%) of the cases had family history of DM. All cases were on daily drug adherence, and most of them (83%) were on regular follow-up. Significant association was observed with urban slum (P = 0.03) and family history of diabetes (P = 0.04) among cases. At the end of continuation phase, 82.8% of the cases were cured and 4.7% of the cases had completed treatment. Conclusion: The study reported 5% of DM among newly registered TB cases and family history of DM as its significant risk factor.
拉杰果德市肺结核患者中糖尿病的患病率、危险因素和治疗结果
背景:结核病(TB)和糖尿病(DM)是世界上主要的公共卫生问题。结核病合并糖尿病会对个体疾病的预后及其治疗效果产生不利影响。材料和方法:在拉杰果德市的五个结核病单位进行了为期五个季度的横断面研究。研究期间新登记的合并糖尿病的肺结核(PTB)患者被纳入病例。治疗结束后随访观察疗效。使用访谈技术以预先测试的形式收集信息。结果:PTB患者中DM患病率为5%。51 ~ 60岁人群(34.4%)最多,男女比例为3:1,生活在城市贫民窟(53.1%),识字(81.2%),中等社会经济阶层(65.6%)。四分之一的病例有结核家族史(28.1%)和既往史(28.1%),超过三分之一(37.5%)的病例有糖尿病家族史。所有病例均坚持每日服药,其中大部分(83%)有定期随访。糖尿病患者与城市贫民窟(P = 0.03)和糖尿病家族史(P = 0.04)有显著相关性。在延续期结束时,82.8%的病例治愈,4.7%的病例完成治疗。结论:研究报告新登记结核病例中糖尿病占5%,糖尿病家族史是其重要危险因素。
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