Effect of levamisole on the immune response of chickens to infection with Eimeria tenella

Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie = International journal of microbiology and hygiene. A, Medical microbiology, infectious... Pub Date : 1984-03-01 DOI:10.1016/S0174-3031(84)80009-8

Hiroshi Onaga , Masanori Tajima , Toshio Ishii

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引用次数: 5

Abstract

The effect of levamisole on the immunization to coccidiosis in chickens was investigated. The protection to the challenge infection with Eimeria tenella was higher in those chickens immunized by inoculating a small number of oocysts of E. tenella and administered orally with levamisole at dosage levels of 1.25 to 5 mg/kg body weight, once daily for 3 days, one week after immunization than in immunized and levamisole-untreated or unimmunized and levamisole-treated chickens.The activities of peritoneal macrophages of chickens from the immunized and levamisole-treated group were higher than those of chickens from the other groups. Futhermore, serum antibody titers and the leucocyte migration inhibitory factor-inducing activities measured in immunized and levamisole-treated chickens reflected the immune state of chickens.

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左旋咪唑对鸡对柔嫩艾美耳球虫感染免疫应答的影响

研究了左旋咪唑对鸡球虫病免疫的影响。接种少量柔嫩艾美耳虫卵囊并口服左旋咪唑(剂量为1.25 ~ 5 mg/kg体重，每天1次，免疫后1周)免疫的鸡对柔嫩艾美耳虫攻毒感染的保护作用高于未接种左旋咪唑或未接种左旋咪唑的鸡。左旋咪唑免疫组和左旋咪唑处理组的腹腔巨噬细胞活性均高于其他各组。免疫和左旋咪唑处理的鸡血清抗体滴度和白细胞迁移抑制因子诱导活性反映了鸡的免疫状态。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie = International journal of microbiology and hygiene. A, Medical microbiology, infectious...

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