The Significance of Performing Osteogenic Differentiation in Human Bone Tissue-Derived Mesenchymal Stromal Cells

Abstract

103 INTRODUCTION Cleft lip/cleft palate (CL/CP) is a congenital abnormality that occurs in approximately 1 in every 500 Japanese infants. Affected patients require multiple surgical procedures with different objectives such as gain-of-function and cosmetic improvement. An important element of treatment for CL/CP is the attainment of normal occlusion. This requires bone formation in the defects of the alveolar cleft along with proper tooth The Significance of Performing Osteogenic Differentiation in Human Bone Tissue-Derived Mesenchymal Stromal Cells