Sequential use of Prepidil and extra-amniotic saline infusion for the induction of labor in nulliparous women with very low Bishop scores.

M. Chammas, Tuan M. Nguyen, R. Vasavada, B. Nuwayhid, L. Castro
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Abstract

Objective : To evaluate the efficacy of sequential use of Prepidil ® (prostaglandin E 2 gel) and extra-amniotic saline infusion for the induction of labor in nulliparous women with very low Bishop scores. Study design : Nulliparous women with singleton gestations, intact membranes and a cervical Bishop score of h 2 who received Prepidil gel and extra-amniotic saline infusion sequentially for the induction of labor between July 1996 and July 1998 were studied. Results : Thirty-one women met the inclusion criteria. Indications for induction included post-dates (six of 31), pre-eclampsia (ten of 31), diabetes (three of 31), oligohydramnios (three of 31), intrauterine growth restriction (two of 31) and non-reactive non-stress test (NST) (seven of 31). The average time from onset of induction to delivery was 38.1 - 13.5 h. Vaginal delivery was achieved in 80.6%. Women requiring >2 doses of Prepidil had a higher risk of delivering abdominally (OR = 3.5). Three of seven (42.9%) women with labor induced fo...
序贯使用Prepidil和羊膜外盐水输注引产的产妇非常低的主教评分。
目的:评价普必地尔(前列腺素e2凝胶)联合羊膜外盐水序贯应用于Bishop评分极低的无产妇女的引产效果。研究设计:研究了1996年7月至1998年7月间连续接受普地尔凝胶和羊膜外盐水输注引产的单胎妊娠、胎膜完整、宫颈Bishop评分为h 2的未生育妇女。结果:31名女性符合纳入标准。引产适应症包括产后(31例中6例)、先兆子痫(31例中10例)、糖尿病(31例中3例)、羊水过少(31例中3例)、宫内生长受限(31例中2例)和非反应性非应激试验(31例中7例)。从引产开始到分娩的平均时间为38.1 ~ 13.5 h,阴道分娩率为80.6%。需要>2剂Prepidil的妇女腹部分娩的风险更高(OR = 3.5)。7名产妇中有3名(42.9%)引产…
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