Contraceptive Vaginal Ring: Nuvaring

Kunal M. Agavane, Sonal B. Ombase
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Abstract

For more than four decades ago, researchers began developing Vaginal contraceptive rings characterized by two guiding principles: the ability vaginal epithelium is made up of a layer of cells that line within the structure vaginal canal ingest the application of steroid ability of elastomers to release hormones at a virtually constant rate. Only two kinds of contraceptive vaginal rings (CVRs) it has been completed to market: NuvaRing, a combination ring that distributes etonogestrel (ENG) and ethinyl estradiol (EE), and Progering, a progesterone-releasing ring for nursing women. The main benefits CVRs are a type of efficacy (tablets are comparable to or slightly superior to), simple to use (no need to remember aa regular schedule), user control over initiation and removal, release rate that is practically constant allowing for flexibility low dosage, greater bioavailability, and excellent cycle control because of the integrated ring. CVRs can produce cervical bleeding and complaints, band expulsion is typical, the ring can During coitus, in addition vaginal implantation can be painful for certain women. CVRs are completely safe, efficacious, Women find it quite appealing, in conformity with studies discussed in this work. CVRs are without a doubt a novel, very efficient contraception for women, expanding their hormonal contraception options.
避孕阴道环:Nuvaring
四十多年前,研究人员开始开发阴道避孕环,其特点是有两个指导原则:阴道上皮是由一层细胞组成的,排列在阴道管道内的结构;使用类固醇;弹性体以几乎恒定的速率释放激素。只有两种避孕阴道环(CVRs)已经投入市场:NuvaRing,一种分配炔诺孕酮(ENG)和炔雌醇(EE)的组合环,以及Progering,一种用于哺乳期妇女的孕酮释放环。cvr的主要优点是疗效(片剂与cvr相当或略优于cvr),使用简单(无需记住常规时间表),用户控制起始和去除,释放率几乎恒定,允许灵活性低剂量,更高的生物利用度,以及由于集成环而具有出色的周期控制。CVRs可引起宫颈出血和不适,带排出是典型的,环可以在性交时,此外,阴道植入对某些女性来说可能会疼痛。cvr是完全安全,有效的,女性认为它很有吸引力,与本工作中讨论的研究一致。毫无疑问,cvr对女性来说是一种新颖、非常有效的避孕方法,扩大了她们的激素避孕选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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