Gender, age and morphofunctional characteristics of the quality of life of patients with stable angina

IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL
V. Tashchuk, T. Amelina, P. R. Ivanchuk, M. A. Ivanchuk
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Abstract

Aim of the work is to investigate the quality of life (QoL) of patients with stable angina pectoris (SA) depending on gender, age distribution and severity of angina pectoris. Materials and methods. 78 patients with an objective diagnosis of functional classes (FC) II–III SA were examined, who formed two clinical groups: the 1st – patients with an increase in QoL (57.69 % of cases), the 2nd – patients with the absence of any changes in QoL (42.31 % of cases). All patients underwent clinical, laboratory, instrumental examinations and determination of QoL using the SF-36 questionnaire. Results. The study of the QoL in men revealed that the mental component (MHC) of health was significantly higher due to such indicators as vitality (VT) (P < 0.001), mental health (MH) (P < 0.001), social functioning (SF) (Р = 0.028), general health status (GHS) (Р < 0.001). Younger age was characterized by a higher physical component of health (PHC) due to significantly higher indicators such as physical functioning (PF) and role-based physical functioning (RBPF) (in both cases P < 0.001). In the subgroup of younger women, the PHC was higher due to significantly higher levels of PF and RBPF (P = 0.048 and P = 0.011, respectively), that could be compared with the indicators of younger men, where the PHC was also higher due to GHS (Р = 0.009), RBPF (P = 0.028) and PF (P = 0.050). In men of younger age, the indicator of VT was significantly higher (Р = 0.031). Patients with higher FC of SA were expected to have a significant limitation of QoL in the form of a lower PHC (GHS (P = 0.023), PF (P < 0.001), RBPF (P < 0.001) and pain intensity (PI) (P < 0.001)). With the progression of heart failure (HF), GHS (P = 0.003), PF (P < 0.001), RBPF (P < 0.001) and PI (P < 0.001) significantly worsened. It was confirmed that the increase of QoL did not depend on gender (women P = 0.204, men P = 0.226) and age (P = 0.143). The presence of excess body weight was characterized by limitation of physical (significantly lower indicators of PF (P = 0.010) and PI (P = 0.008)) and mental (significantly decreased indicator – P = 0.053) health. Conclusions. Positive dynamics of the quality of life is associated with a lower functional class of stable angina pectoris, lower severity of heart failure, favorable shifts in the lipid spectrum, an increase in the left ventricular ejection fraction and the threshold load of cycle ergometry. The physical component of health is decisive in the quality of life of patients with stable angina pectoris.
性别、年龄及形态功能特征对稳定型心绞痛患者生活质量的影响
本研究旨在探讨稳定性心绞痛(SA)患者的生活质量(QoL)与性别、年龄分布和心绞痛严重程度的关系。材料和方法。对78例客观诊断为功能分级(FC) II-III SA的患者进行检查,分为两组:第一组患者生活质量增加(占57.69%),第二组患者生活质量无变化(占42.31%)。所有患者均接受临床、实验室、仪器检查,并采用SF-36问卷测定生活质量。男性生活质量的研究表明,健康的精神成分(MHC)由于活力(VT) (P < 0.001)、心理健康(MH) (P < 0.001)、社会功能(SF) (Р = 0.028)、一般健康状况(GHS) (Р < 0.001)等指标而显著较高。由于身体功能(PF)和基于角色的身体功能(RBPF)等指标明显较高,年龄越小,健康的身体成分(PHC)越高(两种情况下P < 0.001)。在年轻女性亚组中,由于PF和RBPF水平明显较高(P = 0.048和P = 0.011), PHC较高,这可以与年轻男性的指标进行比较,其中PHC也因GHS (Р = 0.009), RBPF (P = 0.028)和PF (P = 0.050)而较高。年轻男性VT指标明显增高(Р = 0.031)。SA FC较高的患者生活质量受到显著限制,表现为PHC较低(GHS (P = 0.023)、PF (P < 0.001)、RBPF (P < 0.001)和疼痛强度(PI) (P < 0.001))。随着心力衰竭(HF)的进展,GHS (P = 0.003)、PF (P < 0.001)、RBPF (P < 0.001)和PI (P < 0.001)均显著恶化。结果表明,生活质量的提高与性别(女性P = 0.204,男性P = 0.226)和年龄(P = 0.143)无关。体重超标的特点是身体(PF指标显著降低(P = 0.010), PI指标显著降低(P = 0.008))和精神健康(P = 0.053)受到限制。生活质量的积极动态变化与稳定性心绞痛的功能等级较低、心力衰竭的严重程度较低、脂质谱的有利变化、左心室射血分数的增加和周期几何的阈值负荷有关。健康的身体成分对稳定型心绞痛患者的生活质量起决定性作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Zaporozhye Medical Journal
Zaporozhye Medical Journal MEDICINE, GENERAL & INTERNAL-
自引率
0.00%
发文量
72
审稿时长
8 weeks
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