Clinico-Functional Characteristics of Left Ventricular Dysfunction in Patients with Glomerulopathies and Their Relationship to Morphological Changes in The Kidneys

Abstract

Purpose: To study the possible association of cardiac function with morphological changes of the kidneys in glomerulopathies. Materials and Methods: 55 patients with GP were examined (32 men, 23 women) aged from 17 to 58 (on the average 32.76 ± 10.3) years. Given the high prevalence left ventricular systolic diastolic dysfunction in patients with GP with impaired renal function, analyzed the data of patients with CKD stages 1-3. The mean GFR was 87.92 ± 28.2 ml / min / 1.73 m2. Histology, immunofluorescence and electron microscopic method of investigation were used in the study of nephrobiopsy data. Results: Analysis of the frequency of morphological types of nephropathy in the examined patients made it possible to detect the prevalence of membranous glomerulonephritis Objective: To study the features of the association of cardiac dysfunction with morphological changes in the kidneys with HP.