Environmentally Benign Mortar-Pestle-Induced Acylation and O-Alkylation of Aromatic and Heteroaromatic Compounds under Solvent-Free Micellar Conditions and Computation of Their Drug Likeliness Properties

Abstract

Environmentally benign mortar-pestle-induced practical methods have been developed for the acylation and O-alkylation of aromatic and heteroaromatic compounds under solventfree micellar conditions, which were found to efficiently afford moderate to excellent yields of products.