Pulmonary changes among asymptomatic smokers using high-resolution computed tomography and pulmonary function tests

IF 0.2 Q4 RESPIRATORY SYSTEM
WalaaG.E. Abo Koura, Ahmed Ali, Mahmoud Elhabashy, D. Serag, SamiS.A. El Dahdouh
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引用次数: 1

Abstract

Objective To detect pulmonary changes among asymptomatic smokers using an inspiratory and expiratory high-resolution computed tomography (HRCT) and pulmonary function tests (PFT). Pulmonary changes associated with smoking are now an increasing public health concern. Computed tomography, especially HRCT, is the best choice for visualizing lung morphology. Patients and methods The study was a cohort study conducted at Shebeen Chest Hospital from January 2019 to January 2021. The study was carried out on 120 adult males; 80 of them were asymptomatic smokers and 40 matched healthy nonsmokers served as the control group. All underwent routine chest radiograph, PA view, HRCT (inspiratory, expiratory) film, and PFTs in the form of forced expiratory vital capacity (FVC), forced expiratory volume after 1 s (FEV1), FEV1/FVC, mean forced expiratory flow, and peak expiratory flow. Comparison between the two groups was done according to HRCT and PFT. Result There was significant difference between inspiratory and expiratory HRCT regarding air trapping between cases. Inspiratory air trapping was present in 4% while expiratory air trapping was present in 18%. There was highly significant difference between cases and controls regarding emphysema and bronchial thickening, subpleural line. There was no statistically significant difference between the two groups regarding FVC, forced expiratory flow 25–75, and FEV1/FVC, while there was a significant difference between them regarding PFT pattern results (P<0.05). Conclusion HRCT is the most sensitive imaging modality for diagnosing early emphysema in asymptomatic smokers. HRCT of the lung can detect lung abnormalities noninvasively.
使用高分辨率计算机断层扫描和肺功能检查无症状吸烟者的肺部变化
目的通过吸气和呼气高分辨率计算机断层扫描(HRCT)和肺功能检查(PFT)检测无症状吸烟者的肺部变化。与吸烟有关的肺部病变现在日益成为公共卫生关注的问题。计算机断层扫描,尤其是HRCT,是观察肺部形态的最佳选择。该研究是一项队列研究,于2019年1月至2021年1月在她比恩胸科医院进行。这项研究对120名成年男性进行了调查;其中80名无症状吸烟者和40名匹配的健康非吸烟者作为对照组。所有患者均接受常规胸片、PA片、HRCT(吸气、呼气)片和pft(用力呼气肺活量(FVC)、1 s后用力呼气量(FEV1)、FEV1/FVC、平均用力呼气流量和呼气峰值)检查。根据HRCT和PFT对两组进行比较。结果不同病例间吸气、呼气HRCT的气阻差异有统计学意义。4%的人存在吸气性气阻,18%的人存在呼气性气阻。在肺气肿、支气管增厚、胸膜下线方面,病例与对照组有显著差异。两组FVC、用力呼气流量25 ~ 75、FEV1/FVC比较,差异均无统计学意义,PFT分型比较,差异均有统计学意义(P<0.05)。结论HRCT是诊断无症状吸烟者早期肺气肿最灵敏的影像学手段。肺部HRCT可以无创地检测肺部异常。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
自引率
0.00%
发文量
46
审稿时长
22 weeks
期刊介绍: The journal will cover technical and clinical studies related to health, ethical and social issues in field of The Egyptian Journal of Chest Diseases and Tuberculosis aims to publish and inform readers and all chest physicians of the progress in medical research concerning all aspect of chest diseases. Publications include original articles review articles, editorials, case studies and reports which are relevant to chest diseases. The Journal also aims to highlight recent updates in chest medicine. . Articles with clinical interest and implications will be given preference.
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