STUDY OF THE SIZE OF THE DISPERSED PHASE OF SELF-STABILIZED AQUEOUS DISPERSION OF PHOSPHORUS-CONTAINING POLYESTERS

Abstract

New phosphorus-containing polyesters based on N-derivatives of dicarboxylic α-amino acids and diols of the polyoxyethylene series in which the phosphate group has been introduced are synthesized, capable of forming self-stabilized dispersions with nanosized particles of the dispersed phase in aqueous media. The introduction of the phosphate group in the hydrophilic fragment significantly increases the stabilizing ability. The properties of new phosphorus-containing polyesters allow us to consider them as potential systems for drug delivery.