SERUM RIBONUCLEASE DURING THE PROCESS OF DAB CARCINOGENESIS AND TUMOR GROWTH.

Abstract

The activity of serum ribonuclease (RNase) of rats fed a diet containing 4-dimethylaminoazobenzene was depressed by 50–60% at the third week of feeding compared to that of control rats fed the basal diet alone for the same period of time. Tumor cells of the Novikoff hepatoma contained 7–8% of the RXase activity of normal liver cells.