Pratik P. Maske, Sachin G. Lokapure, Dhanashri Nimbalkar, Shobharaj Malavi, John I. D'souza
{"title":"In vitro determination of sun protection factor and chemical stability of Rosa kordesii extract gel","authors":"Pratik P. Maske, Sachin G. Lokapure, Dhanashri Nimbalkar, Shobharaj Malavi, John I. D'souza","doi":"10.1016/j.jopr.2013.05.021","DOIUrl":null,"url":null,"abstract":"<div><h3>Aims</h3><p>In the present study, to investigate its chemical stability and the in vitro sun protection factor (SPF) of <em>Rosa kordesii</em> petal extract in a gel formulation.</p></div><div><h3>Methods</h3><p>Due to its antioxidant and photoprotective properties, <em>R. kordesii</em> is a promising candidate for use in cosmetic and pharmaceutical formulations. A high performance liquid chromatography method was used to evaluate the chemical stability using <em>R. kordesii</em> extract as marker at 5, 25 and 45 °C for 3–4 months. The sun protection factors were analyzed by ultraviolet (UV) spectrophotometry using samples irradiated with UVB lamp.</p></div><div><h3>Results</h3><p>The chemical stability of the <em>R. kordesii</em> root extract gel was determined according to the concentration of <em>R. kordesii</em> extracts at different storage temperatures (5, 25 and 45 °C) for 3–4 months. It is screened for in vitro sun protection factor in the <em>R. kordesii</em> extract and of its gel formulation and determines Photostability of the isolated <em>R. kordesii</em> extract and SPF.</p></div><div><h3>Conclusion</h3><p>This study has shown that the <em>R. kordesii</em> petal extract gel is stable for at least 3–4 months when stored at 5 and 25 °C. It is essential for collection of similar data for different plants and their flowers, as well as other parts. This proved activity of plant showed its importance and prophylactic utility in anti-solar formulation. This will be a better, cheaper and safe alternative to harmful chemical sunscreens that used now a days in the industry.</p></div>","PeriodicalId":16787,"journal":{"name":"Journal of Pharmacy Research","volume":"7 6","pages":"Pages 520-524"},"PeriodicalIF":0.0000,"publicationDate":"2013-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jopr.2013.05.021","citationCount":"29","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pharmacy Research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0974694313002697","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 29
Abstract
Aims
In the present study, to investigate its chemical stability and the in vitro sun protection factor (SPF) of Rosa kordesii petal extract in a gel formulation.
Methods
Due to its antioxidant and photoprotective properties, R. kordesii is a promising candidate for use in cosmetic and pharmaceutical formulations. A high performance liquid chromatography method was used to evaluate the chemical stability using R. kordesii extract as marker at 5, 25 and 45 °C for 3–4 months. The sun protection factors were analyzed by ultraviolet (UV) spectrophotometry using samples irradiated with UVB lamp.
Results
The chemical stability of the R. kordesii root extract gel was determined according to the concentration of R. kordesii extracts at different storage temperatures (5, 25 and 45 °C) for 3–4 months. It is screened for in vitro sun protection factor in the R. kordesii extract and of its gel formulation and determines Photostability of the isolated R. kordesii extract and SPF.
Conclusion
This study has shown that the R. kordesii petal extract gel is stable for at least 3–4 months when stored at 5 and 25 °C. It is essential for collection of similar data for different plants and their flowers, as well as other parts. This proved activity of plant showed its importance and prophylactic utility in anti-solar formulation. This will be a better, cheaper and safe alternative to harmful chemical sunscreens that used now a days in the industry.