Afrim Zeqiraj, Zafer Gashi, Sadi Bexheti, S. Elezaj, S. Berisha, A. Shabani
{"title":"Obesity and Male Infertility in The Dukagjin Region in Republic of Kosovo","authors":"Afrim Zeqiraj, Zafer Gashi, Sadi Bexheti, S. Elezaj, S. Berisha, A. Shabani","doi":"10.21767/2248-9215.100035","DOIUrl":null,"url":null,"abstract":"In this paper will be studied the causes that can cause \n overweight in men, and the disorder of hormone \n production from endocrine glands, as well as the influence \n of obesity in infertility. Purpose of the work, it is to \n determine the degree of male infertility by overweight men. \n The work was done in the region of Peja, in the Republic of \n Kosovo. Materials and methods, the sampling was done in \n March 2015-March 2017 in the Biolab-Zafi endocrinology \n laboratory in Peja, Republic of Kosovo. Our results show a \n significant increase in male infertility rates with BMI 29.97 ± \n 3.22, compared with men with BMI 23.52 ± 2.0 (p<0.00001). \n We also found a significant increase in working group rates \n with FSH 7.99 ± 8.21, compared to control group FSH 4.72 ± \n 2.63 (p<0.008). We also found a significant increase in \n working group rates with LH 5.06 ± 2.74, compared to \n control group LH 3.79 ± 1.99 (p<0.002). We also found a \n significant increase in working group rates with Prolactin \n 17.37 ± 7.66, compared to control group Prolacitn 13.05 ± \n 4.8 (p<0.00004). We also found a significant increase in \n working group rates with Testosterone 4.16 ± 1.88, \n compared to control group Testosterone 5.79 ± 1.48 \n (p<0.005). Conclusion, the results from this study show that \n obesity in our country, the Republic of Kosovo, is a growing \n problem in the development of public health, and is an \n important risk factor for the appearance of male infertility. \n The effects of BMI growth tend to increase the risk of DNA \n damage in ejaculates, increase in hormone levels (FSH, LH, \n prolactin, testosterone), decrease sperm parameters \n (decrease in number, decrease in movement), oxidative \n stress, Risk of hypertension, cardiac disorders, diabetes and \n other chronic disorders.","PeriodicalId":12012,"journal":{"name":"European Journal of Experimental Biology","volume":"13 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Experimental Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21767/2248-9215.100035","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
In this paper will be studied the causes that can cause
overweight in men, and the disorder of hormone
production from endocrine glands, as well as the influence
of obesity in infertility. Purpose of the work, it is to
determine the degree of male infertility by overweight men.
The work was done in the region of Peja, in the Republic of
Kosovo. Materials and methods, the sampling was done in
March 2015-March 2017 in the Biolab-Zafi endocrinology
laboratory in Peja, Republic of Kosovo. Our results show a
significant increase in male infertility rates with BMI 29.97 ±
3.22, compared with men with BMI 23.52 ± 2.0 (p<0.00001).
We also found a significant increase in working group rates
with FSH 7.99 ± 8.21, compared to control group FSH 4.72 ±
2.63 (p<0.008). We also found a significant increase in
working group rates with LH 5.06 ± 2.74, compared to
control group LH 3.79 ± 1.99 (p<0.002). We also found a
significant increase in working group rates with Prolactin
17.37 ± 7.66, compared to control group Prolacitn 13.05 ±
4.8 (p<0.00004). We also found a significant increase in
working group rates with Testosterone 4.16 ± 1.88,
compared to control group Testosterone 5.79 ± 1.48
(p<0.005). Conclusion, the results from this study show that
obesity in our country, the Republic of Kosovo, is a growing
problem in the development of public health, and is an
important risk factor for the appearance of male infertility.
The effects of BMI growth tend to increase the risk of DNA
damage in ejaculates, increase in hormone levels (FSH, LH,
prolactin, testosterone), decrease sperm parameters
(decrease in number, decrease in movement), oxidative
stress, Risk of hypertension, cardiac disorders, diabetes and
other chronic disorders.