Outbreak of Neonatal Staphylococcal Scalded Skin Syndrome in a Maternal Unit

Q4 Medicine

Perinatology Pub Date : 2021-06-01 DOI:10.14734/pn.2021.32.2.61

Y. Jeon, Yunha Hwang, Yejin Park, C. Kim, R. Lim

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引用次数: 0

Abstract

Objective: Staphylococcal scalded skin syndrome (SSSS) is a relatively rare superficial blistering skin disease caused by exfoliating toxins produced by Staphylococcus aureus. We experienced a 3-month outbreak of neonatal SSSS in a maternal unit. Methods: The medical records of newborns who were diagnosed with SSSS were retrospectively reviewed. Results: Eleven newborns with SSSS were transferred to our hospital between January and March 2019. The median age of the newborns was 18.0 (11.0-22.5) days. Of the 11 newborns, 2 (18%) showed the generalized type of SSSS, 4 (36%) the intermediate type, and 5 (45%) the abortive type. S. aureus was isolated in 10 of the newborns and found to be methicillin-resistant in 9 cases. All the newborns were treated with intravenous cefazolin, and two newborns with the generalized type were also treated with clindamycin. The median duration of antibiotic use is 8 (6-14) days. All the newborns responded well to antibiotics and were discharged without complications. Conclusion: We recently experienced an outbreak of neonatal SSSS. To manage problems associated with such an outbreak, periodic monitoring is required, along with guidelines for infection control, such as thorough infection education, isolation of infected newborns, and antiseptic handwashing.

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新生儿葡萄球菌烫伤皮肤综合征暴发在产妇单位

目的:葡萄球菌性烫伤皮肤综合征(SSSS)是由金黄色葡萄球菌产生的去角质毒素引起的一种较为罕见的浅表疱性皮肤病。我们在一个产妇病房经历了3个月新生儿SSSS的爆发。方法:对诊断为SSSS的新生儿病历进行回顾性分析。结果:2019年1月至3月，11例SSSS新生儿转至我院。新生儿的中位年龄为18.0(11.0-22.5)天。11例新生儿中，2例(18%)为广义型，4例(36%)为中间型，5例(45%)为流产型。10例新生儿分离出金黄色葡萄球菌，9例对甲氧西林耐药。所有新生儿均静脉滴注头孢唑林，2例广泛性新生儿同时滴注克林霉素。抗生素使用的中位持续时间为8(6-14)天。所有新生儿对抗生素反应良好，出院时无并发症。结论:我们最近经历了新生儿SSSS的爆发。为管理与此类暴发有关的问题，需要进行定期监测，并制定感染控制指南，例如全面的感染教育、隔离受感染的新生儿和消毒洗手。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Perinatology Medicine-Obstetrics and Gynecology

CiteScore

0.10

自引率

0.00%

发文量

期刊介绍： Perinatology - Journal of Perinatal and Neonatal Care (ISSN 0972-2408), one of the few journals dedicated to the emerging multidisciplinary field of perinatal medicine, is published and distributed quarterly by The Himalaya Drug Company (Bengaluru, Karnataka, India). Perinatology publishes original research articles, review articles, brief reports on clinical and laboratory observations, case reports, and clinical studies.