URINALYSIS AS PREDICTOR OF UPPER-TRACT URINARY STONE ON COLIC PAIN PATIENTS: SINGLE-CENTER COHORT STUDY

Edi Wibowo, P. Satyagraha, B. Daryanto
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Abstract

Objective: There was no study in our country especially in our hospital that studied correlation between urinalysis and upper tract urinary stone on colic pain patients, so we conducted the study. Material & Methods: We_collected patients' data with colic abdomen from January 2018 to January 2020 then divided into hematuria and non-hematuria group respectively. We excluded patients with lower-tract urinary stones, DJ-stent insitu, BPH, and malignancy. All patients had urinalysis and abdominal ultrasound, then continued with non-contrast abdominal CT-Scan or Intravenous Urography. Retrospective and prospective cohort study was performed to collect data: age, sex, serum ureum and creatinine, urinalysis results (pH, specific gravity, nitric, leucocyte, erythrocyte, crystal, and bacteria), stone number, site, and size, then analysed the relationship between urinalysis results with upper-tract urinary stone incidence using point biserial correlation. Results: We found 235 colic patients, 115 and 120 patients in hematuria and non-hematuria group respectively. Male patients were higher, 137_(58.3%). The highest incidence was in the range 41-50 years-old_(30.6%), mean 46.5313,53 years-old. Stone incidence was 55.7% in all colic patients. Stone was proven 78.3% and 34.2% in hematuria and non-hematuria group respectively. There was significant association between upper-tract urinary stone and haematuria compared to non-haematuria patients (p<0.05). Relative-risk (RR) was 2.29, CI_95%. Conclusion: Hematuria increases two-folds probability of upper-tract urinary stone. It is necessary to expand population data and follow-up center to make this representative
尿分析作为绞痛患者上尿路结石的预测因素:单中心队列研究
目的:在我国,特别是我院尚无关于绞痛患者尿检与上尿路结石相关性的研究,故进行研究。材料与方法:我们收集2018年1月至2020年1月期间腹绞痛患者的资料,并将其分为血尿组和非血尿组。我们排除了患有下路尿路结石、原位dj支架、BPH和恶性肿瘤的患者。所有患者进行尿液分析和腹部超声检查,然后继续进行非对比腹部ct扫描或静脉尿路造影。采用回顾性和前瞻性队列研究,收集年龄、性别、血清尿素和肌酐、尿分析结果(pH、比重、一氧化氮、白细胞、红细胞、晶体、细菌)、结石数量、部位、大小等资料,采用点双列相关分析尿分析结果与上尿路结石发病率的关系。结果:有血尿组和无血尿组绞痛患者分别为235例、115例和120例。男性患者较多,为137例(58.3%)。发病率以41 ~ 50岁最高(30.6%),平均46.5313岁,53岁。所有绞痛患者结石发生率为55.7%。血尿组和非血尿组结石发生率分别为78.3%和34.2%。与非血尿患者相比,上尿路结石与血尿有显著相关性(p<0.05)。相对危险度(RR)为2.29,CI_95%。结论:血尿使上尿路结石发生的可能性增加2倍。有必要扩大人口数据和随访中心,使其具有代表性
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