Effects of Ethanolic Leaf Extract of Solenostemon Monostachyus on Blood Glucose level and Histopathological Parameter in STZ induced Diabetic Wistar Albino Rats

Abstract

One of the most dangerous and life threatening diseases in the world today, involving the pancreas, is diabetes mellitus [1]. It is a condition primarily defined by the level of hyperglycemia giving rise to risk of micro vascular damage (retinopathy, nephropathy and neuropathy). It is associated with reduced life expectancy, significant morbidity due to specific diabetes related micro vascular complications, increased risk of macro vascular complications (ischemic heart disease, stroke and peripheral vascular disease) and diminished quality of life [2]. The record of its prevalence in the world today and the increase in morbidity and mortality rates calls for an urgent attention from the health professionals and policy makers in tackling this disease. In CôtedIvoire, the rate of morbidity is 5.7%. Traditional medical herbs used for strengthening the body immune system and for therapeutic purposes are known to have many essential and nutritional elements. Many plants have been documented to have the efficacy to treat diabetes in CôtedIvoire [3].