A Novel Dementia Scale for Alzheimer's Disease

Takashi Kikuchi, Takahiro Mori, K. Wada-isoe, Y. Umeda-Kameyama, T. Kagimura, S. Kojima, M. Akishita, Yu Nakamura
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引用次数: 11

Abstract

Objective: We established the diagnostic accuracy of the “ABC Dementia Scale” (ABC-DS) for Alzheimer’s disease (AD), which concurrently assesses activities of daily living (“A”), behavioral and psychological symptoms of dementia (“B”), and cognitive function (“C”), using a novel scoring approach called the three-dimensional distance (TDD). Methods: The ABC-DS has 13 items with nine ordered categorical levels. Caregivers were interviewed using a semi-structured interview. The construct validity, concurrent validity, test-retest reliability, and responsiveness (score changes over 12 weeks) were assessed. Results: We enrolled 63 participants with probable AD as well as 88, 106, and 55 patients with mild, moderate, and severe AD, respectively. The construct and concurrent validities of each domain score were determined. The TDD accurately discriminated the AD stages and detected score changes indicating disease progression over 12 weeks. Conclusion: The ABC-DS is stable, accurately stages AD severity, and monitors disease progression. The TDD is a useful algorithm for detecting disease progression.
一种新的阿尔茨海默病痴呆量表
目的:我们建立了“ABC痴呆量表”(ABC- ds)对阿尔茨海默病(AD)的诊断准确性,该量表同时评估日常生活活动(“A”)、痴呆的行为和心理症状(“B”)和认知功能(“C”),采用一种称为三维距离(TDD)的新颖评分方法。方法:ABC-DS量表共13项,分为9个有序分类层次。对护理人员进行半结构化访谈。评估构念效度、并发效度、重测信度和反应性(12周内得分变化)。结果:我们招募了63名可能患有阿尔茨海默病的参与者,以及88名、106名和55名轻度、中度和重度阿尔茨海默病患者。确定各领域评分的结构和并发效度。TDD准确地区分了AD的分期,并检测到12周内指示疾病进展的评分变化。结论:ABC-DS是稳定的,可以准确地分期AD的严重程度,并监测疾病的进展。TDD是一种检测疾病进展的有用算法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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