Epidemiology of particulate air pollution: exploiting observable exposure variability

C. Pope
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Abstract

Epidemiological studies of PM pollution and health have attempted to exploit observable sources of exposure variability to evaluate potential health consequences. These studies have become increasingly ingenious and rigorous in their ability to use natural exposure variability. Although a large majority of studies have evaluated only changes in short-term exposures, long-term, chronic exposure may be more important in terms of overall public health. This paper outlines the various dimensions of natural PM exposure variability that have been exploited in the epidemiology of PM literature, discuss how this exposure variablilty has or has not been utilized in recent epidemiology studies of PM exposure and human health, outline the inferences being drawn from the studies, and present the major limitations of these studies.Copyright © 1999 John Wiley & Sons, Ltd.
微粒空气污染的流行病学:利用可观察到的暴露变异性
关于PM污染与健康的流行病学研究试图利用可观察到的暴露变异性源来评估潜在的健康后果。这些研究在利用自然暴露变异性的能力方面变得越来越巧妙和严格。虽然绝大多数研究只评估了短期接触的变化,但就整体公共卫生而言,长期、慢性接触可能更为重要。本文概述了在PM流行病学文献中利用的自然PM暴露变异性的各个方面,讨论了在最近的PM暴露与人类健康的流行病学研究中如何利用或未利用这种暴露变异性,概述了从研究中得出的推论,并提出了这些研究的主要局限性。版权所有©1999 John Wiley & Sons, Ltd
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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