Current issues of ophthalmic rheumatology

Abstract

Ablepsia and hypovision as a social medical problem occupies one of the leading places, both in health care and the economy of the state. Uveitis associated with systemic diseases occur in up to 40% of the population and require an interdisciplinary approach, as they are characterized by polymorphism of clinical manifestations, which makes it difficult to diagnose and treat early, leads to rapid development of complications and disability. Aim. Analysis of literature data on epidemiological and clinical features of uveitis associated with systemic diseases. Material and methods. To analyze the literature, we searched for information about this problem for a period up to 10 years in PubMed/ MEDLINE, PMC, Web of Since. The following terms were used separately or in combination for the search: “uveitis”, “non-infectious uveitis”, “spondylarthritis”, “systemic connective tissue diseases”, “systemic vasculitis”, “complications”, “anti-TNF-α”. The search criteria were key studies related to uveitis and systemic diseases: meta-analyses, original studies, retrospective and cohort studies. Results and discussion. In everyday clinical practice, only close cooperation between rheumatologist and ophthalmologist considering carefully collected anamnestic information, clinical features and course of disease, data of additional examinations contribute to early diagnosis, selection of optimal strategy of treatment, prevention of recurrence and the reduction of visual impairment. Conclusion. All patients with ocular inflammation, especially in the presence of systemic diseases, require the professional attention of clinical medicine specialists. Keywords: inflammatory eye diseases, uveitis, systemic diseases, complications, spondylarthritis, systemic vasculitis, Behcet's syndrome, SLE.