Primary PCI in Patients Admitted with Cardiogenic Shock and STEMI: Outcome and Predictors of In-hospital Mortality

Mohamed Elsayed Abderhman, Ahmed Abdelhameed Rozza, Mostafa Mokarrab, Samir Mostafa Kotb Hatem
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Abstract

: Background : It is a well-known phenomenon that cardiogenic shock (CS) is a serious complication of acute myocardial infarction. The mortality rate is approximately 50% even with rapid revascularization, optimal medical care, and use of mechanical support. Aim of the Work : To investigate the outcome of primary percutaneous coronary intervention (PCI) in patients admitted with cardiogenic shock and ST-segment elevation myocardial infarction (STEMI) and the predictors of in-hospital mortality. Patients and Methods : This prospective, observational study was conducted in the national heart Institute, Alazhar University, and Military hospitals in the period from 6/2019 to 9/2021 on fifty six consecutive patients presenting to Alazhar University hospitals, National Heart Institute (NHI), Military hospitals. Results : The prevalence of dyslipidemia and diabetes mellitus were significantly higher among died patients than those who survived. The degree of LV impairment was significantly higher among patients who died than those who survived. As regard to PCI procedure characteristics, TIMI flow post PCI (
心源性休克和STEMI患者的首次PCI治疗:院内死亡率的结局和预测因素
背景:心源性休克是急性心肌梗死的严重并发症,这是一个众所周知的现象。即使采用快速血运重建、最佳医疗护理和机械支持,死亡率仍约为50%。研究目的:探讨心源性休克合并st段抬高型心肌梗死(STEMI)患者经皮冠状动脉介入治疗(PCI)的预后及院内死亡率的预测因素。患者和方法:本前瞻性观察性研究于2019年6月至2021年9月在阿拉资哈尔大学国立心脏研究所和军队医院进行,对56名连续在阿拉资哈尔大学医院、国家心脏研究所(NHI)和军队医院就诊的患者进行研究。结果:死亡患者血脂异常及糖尿病患病率明显高于存活患者。死亡患者的左室损伤程度明显高于存活患者。在PCI手术特点方面,PCI术后TIMI血流(< III级)、多血管病变、手术失败与院内高死亡率显著相关。接受IABP治疗的患者明显年龄较大。结论:多支冠状动脉疾病、PCI术后TIMI血流(III级)和↑CK-MB(72小时连续测量)均是院内死亡率的重要预测因素。从胸痛到ED到达的时间和从门到球囊的时间都比以往研究报道的要长。未发现IABP的使用对STEMI患者的不同结局有显著的预测作用。
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