Quetiapine versus risperidone in the pharmacotherapy of behavioral and psychological symptoms of dementia: an open labelled study

Abstract

Dementia syndrome is characterized by a progressive deterioration of cortical functioning including language, judgment , comprehension, memory, thinking and new learning.1 Dementia is common among patients with neurodegenerative disorders and substance abuse.2 In Asia pacific region the prevalence of dementia in 2015 is 23 million.1 Dementia syndrome consists of behavioral and psychological symptoms (BPSD) such as non-cognitive disturbances including affective symptoms like anxiety, depression, irritability, psychotic symptoms like delusions, hallucinations ,behavioral disorders like insomnia, wandering, aggression, agitation, eating and sexual disorders.3