THE RELEASE OF FLUORIDE IONS OF BIOACTIVE RESIN IN THE SOLUTION OF LACTIC ACID AND ARTIFICIAL SALIVA

Dewi Puspitasari, Nadya Fatimah Alzahrah, Indri Indah Tari, D. Wibowo, Rahmad Arifin, Renie Kumala Dewi, S. Diana
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Abstract

Background: Bioactive resin can release fluoride ions when contact with oral environment. In the oral cavity, saliva and metabolic results of Streptococcus mutans namely lactic acid may affect the release of ions due to pH changes. Purpose: to analyse the release of fluoride ions of bioactive resin in the solution of lactic acid and artificial saliva. Methods: Forty-two specimens (diameter 15 mm x thickness 1 mm; n= 7/group fabricated with Activa™ Bioactive Restorative (Pulpdent). The specimen swere randomized into six 6 groups which immersed in lactic acid, artifial saliva and distilled water for 1 and 7 days in the incubator at 37oC. The number of fluoride ion release was measured using pH Meter (Lutron-208). Results: Two Way Anova test and Post Hoc Bonferonni test show there are significant differences among all group for lactic acid 1 day (6.37 ± 0.74), artificial saliva 1 day (1.30 ± 0.48), distilled water 1 day (3.78 ± 0.97), lactic acid 7 days (22.9 ± 0.81), artificial saliva 7 days (19.00 ± 0.81), distilled water 7 days (21.60± 1.01) ppm. Conclusion: The fluoride ion release of bioactive resin which immersed in lactic acid solution was higher than in artificial saliva immersion.  Keywords: Artificial saliva, Bioactive resin, Fluoride ion release, Lactic acid
生物活性树脂在乳酸和人工唾液溶液中氟离子的释放
背景:生物活性树脂与口腔环境接触可释放氟离子。在口腔内,唾液和变形链球菌的代谢结果即乳酸可能由于pH值的变化而影响离子的释放。目的:分析生物活性树脂在乳酸和人工唾液溶液中氟离子的释放情况。方法:42例标本(直径15mm x厚度1mm;n= 7/组用Activa™Bioactive Restorative (pulp)制成。将标本随机分为6组,分别在37℃的培养箱中浸泡乳酸、人工唾液和蒸馏水1天和7天。用pH计(Lutron-208)测定氟离子释放数。结果:双因素方差分析和事后Bonferonni检验显示,乳酸1天(6.37±0.74)、人工唾液1天(1.30±0.48)、蒸馏水1天(3.78±0.97)、乳酸7天(22.9±0.81)、人工唾液7天(19.00±0.81)、蒸馏水7天(21.60±1.01)ppm各组间差异有统计学意义。结论:乳酸溶液浸泡生物活性树脂的氟离子释放量高于人工唾液浸泡。关键词:人工唾液;生物活性树脂;氟离子释放
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