Comparison of the hypothetical 57Co brachytherapy source with the 192Ir source

M. Toossi, M. Ghorbani, A. Rostami, M. Khosroabadi, S. Khademi, C. Knaup
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引用次数: 2

Abstract

Aim of the study The 57Co radioisotope has recently been proposed as a hypothetical brachytherapy source due to its high specific activity, appropriate half-life (272 days) and medium energy photons (114.17 keV on average). In this study, Task Group No. 43 dosimetric parameters were calculated and reported for a hypothetical 57Co source. Material and methods A hypothetical 57Co source was simulated in MCNPX, consisting of an active cylinder with 3.5 mm length and 0.6 mm radius encapsulated in a stainless steel capsule. Three photon energies were utilized (136 keV [10.68%], 122 keV [85.60%], 14 keV [9.16%]) for the 57Co source. Air kerma strength, dose rate constant, radial dose function, anisotropy function, and isodose curves for the source were calculated and compared to the corresponding data for a 192Ir source. Results The results are presented as tables and figures. Air kerma strength per 1 mCi activity for the 57Co source was 0.46 cGyh–1 cm 2 mCi–1. The dose rate constant for the 57Co source was determined to be 1.215 cGyh–1U–1. The radial dose function for the 57Co source has an increasing trend due to multiple scattering of low energy photons. The anisotropy function for the 57Co source at various distances from the source is more isotropic than the 192Ir source. Conclusions The 57Co source has advantages over 192Ir due to its lower energy photons, longer half-life, higher dose rate constant and more isotropic anisotropic function. However, the 192Ir source has a higher initial air kerma strength and more uniform radial dose function. These properties make 57Co a suitable source for use in brachytherapy applications.
假设的57Co近距离治疗源与192Ir源的比较
57Co放射性同位素由于其高比活度、适当的半衰期(272天)和中等能量光子(平均114.17 keV),最近被提议作为一种假设的近距离治疗源。在本研究中,对假设的57Co源计算并报告了43号任务组的剂量学参数。材料和方法在MCNPX中模拟了一个假想的57Co源,该源由一个长3.5 mm、半径0.6 mm的活性圆柱体封装在不锈钢胶囊中组成。57Co源利用了3种光子能量(136 keV [10.68%], 122 keV [85.60%], 14 keV[9.16%])。计算了该源的空气强度、剂量率常数、径向剂量函数、各向异性函数和等剂量曲线,并与192Ir源的相应数据进行了比较。结果实验结果以图表形式呈现。57Co源每1 mCi活性的空气kerma强度为0.46 cGyh-1 cm 2 mCi - 1。57Co源的剂量率常数为1.215 cGyh-1U-1。由于低能光子的多次散射,57Co源的径向剂量函数有增大的趋势。57Co源在不同距离处的各向异性函数比192Ir源更各向同性。结论57Co源具有光子能量低、半衰期长、剂量率常数高、各向同性各向异性功能强等优点。然而,192Ir源具有更高的初始气流强度和更均匀的径向剂量函数。这些特性使57Co成为近距离治疗应用的合适来源。
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