Assessment and management of human health risk from biocides

Abstract

The assessment and management of human health risk from biocides is an iterative and multidisciplinary scientific process that seeks to define the inherent hazards of the material and integrate this information with the details of potential human exposure. This paper attempts to outline the critical elements and relationships in this process while presenting the risk assessment process for Kathon microbicides (blend of isothiazolones, 3:1 ratio of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one: MCI/MC) as an illustrative example.