Profile of HIV/AIDS Patients Coinfected with Tuberculosis in Bumi Wonorejo Health Centre and Santo Rafael Clinic Nabire, Papua

T. N. Kridaningsih, M. Widiyanti, S. Adiningsih, H. Hutapea, E. Fitriana, Evi Iriani Natalia
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引用次数: 1

Abstract

HIV-TB co-infection still becomes a health problem in Indonesia, including in Nabire district, Papua province, which has the highest number of cases. HIV and TB infections are closely related and affect the epidemiology of one another. This study aims to determine the profile description of HIV-TB co-infected patients in Nabire. This research is a descriptive study with a cross-sectional design on 90 people with HIV/AIDS selected consecutively. Data were analyzed univariately and presented in the form of a frequency distribution table. The results showed that of 55 HIV/AIDS co-infected TB patients, almost all (90.9%) were Papuan ethnic, 70.9% were female and aged 30 to 49 years (50.9%) with a mean of 31.309.36 years. The majority of HIV-TB co-infected patients were married (63.6%), holding secondary education (58.2%), working (67.3%), engaging in sexual activity after 17 years of age, only having one sexual partner, and did not use drugs or obtain blood transfusions. The clinical profile of HIV-TB patients showed that 67.3% of the patients were with baseline CD4 count ≤350 cells/mm3, 64.8% had CD4 count at the time of study >350 cells/mm3, and viral load values fewer than 5000 copies/ml (87.3%). The therapy most widely received for patients with HIV-TB coinfection was the combination of ARV 3TC+EFV+TDF (76.4%). The most common clinical symptoms of HIV/AIDS patients were weight loss (56.4%), cough (40%), recurrent oral thrush (36.4%), chickenpox (32.7%), and tuberculosis lymph nodes (18.2%).
巴布亚Bumi Wonorejo保健中心和圣拉斐尔诊所合并感染结核病的艾滋病毒/艾滋病患者概况
艾滋病毒-结核病合并感染仍然是印度尼西亚的一个卫生问题,包括在病例数量最多的巴布亚省Nabire区。艾滋病毒和结核病感染密切相关,相互影响流行病学。本研究旨在确定纳比雷地区HIV-TB合并感染患者的概况描述。本研究采用横断面设计的描述性研究,连续选取90例HIV/AIDS感染者。对数据进行单变量分析,并以频率分布表的形式呈现。结果显示,55例HIV/AIDS合并感染结核患者中,巴布亚族几乎全部(90.9%),女性70.9%,年龄30 ~ 49岁(50.9%),平均年龄为31.309.36岁。大多数艾滋病毒-结核病合并感染患者已婚(63.6%),受过中等教育(58.2%),有工作(67.3%),17岁以后有性行为,只有一个性伴侣,不使用药物或接受输血。HIV-TB患者的临床资料显示,67.3%的患者基线CD4计数≤350细胞/mm3, 64.8%的患者在研究时CD4计数>350细胞/mm3,病毒载量值小于5000拷贝/ml(87.3%)。HIV-TB合并感染患者最广泛接受的治疗是ARV 3TC+EFV+TDF联合治疗(76.4%)。HIV/AIDS患者最常见的临床症状为体重减轻(56.4%)、咳嗽(40%)、复发性鹅口疮(36.4%)、水痘(32.7%)和结核性淋巴结(18.2%)。
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