Acrylic-Based Materials for Biomedical and Bioengineering Applications

Ã. Serrano-Aroca, S. Deb
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引用次数: 2

Abstract

Acrylic-based polymers have been used for many years in biomedical applications because of their versatile properties. Many different polymers belong to this class of polymers, of which a significant number have been approved by the US Food and Drug Administration (FDA) and are frequently used in ophthalmologic devices, orthopaedics, tissue engineering applications and dental applications. The applications of this class of polymers have the potential to be expanded exponentially in the biomedical industry if their properties such as mechanical performance, electrical and/or thermal properties, fluid diffusion, biological behaviour, antimicrobial capacity and porosity can be tailored to specific requirements. Thus, acrylic-based materials have been produced as multicomponent polymeric platforms as interpenetrating polymer networks or in combination with other sophisticated materials such as fibres, nanofibres, carbon nanomaterials such as graphene and its derivatives and/or many other types of nanoparticles in the form of composite or nanocomposite biomaterials. Moreover, in regenerative medicine, acrylic porous supports (scaffolds) need to be structured with the necessary degree, type and morphology of pores by advanced technological fabrication techniques.
生物医学和生物工程应用的丙烯酸基材料
丙烯酸基聚合物由于其多用途的特性已在生物医学领域应用多年。许多不同的聚合物属于这类聚合物,其中相当一部分已被美国食品和药物管理局(FDA)批准,并经常用于眼科设备,骨科,组织工程应用和牙科应用。如果这类聚合物的机械性能、电气和/或热性能、流体扩散、生物行为、抗菌能力和孔隙度等性能可以根据特定要求进行定制,那么它们在生物医学行业的应用将有可能呈指数级增长。因此,丙烯酸基材料已被生产为多组分聚合物平台,如互穿聚合物网络,或与其他复杂材料(如纤维、纳米纤维、碳纳米材料(如石墨烯及其衍生物)和/或许多其他类型的复合材料或纳米复合生物材料)相结合。此外,在再生医学中,丙烯酸多孔支架(支架)需要通过先进的工艺制造技术来构造具有必要的孔隙度、类型和形态。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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