Association of Anemia with Chronic Kidney Disease: A Tertiary Care Hospital Based Cross Sectional Study

Talha Yousuf, Md Shamim Ahmed, M. Hasan, Md Shafiqul Islam
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Abstract

Background: Chronic kidney disease (CKD) is a worldwide public health problem. It is usually associated with anemia and prevalence of anemia increases progressively with worsening CKD. Objective: To find out the association of anemia with different stages of CKD. Materials and Methods: This cross-sectional study was conducted in the department of physiology in Mymensingh medical college, Bangladesh over a period of one year from January to December 2016. A total number of 174 subjects were enrolled in this study among which 87 patients and 87 healthy participants. On the basis of inclusion and exclusion criteria study subjects were divided into case and control group. Hemoglobin concentrations in the blood were measured in all study subjects by using auto-analyzer. Result: Hemoglobin concentration in the blood was decreased in both male and female CKD patients which were 9.55±1.13 gm/dl and 9.11±0.95 gm/dl respectively and result was statistically significant (p<0.01).) 55% is anemic in stage 1, 61% in stage 2, 70% in stage 3, 75% in stage 4, 86% in stage 5 of CKD. Conclusion: This study revealed that prevalence of anemia is common in all stages of CKD patients in Mymensingh, Bangladesh. It emphasizes the need for regular checking of anemia in CKD patients and early referral to the nephrologists. KYAMC Journal. 2022;12(04): 218-221
贫血与慢性肾脏疾病的关联:基于三级医院的横断面研究
背景:慢性肾脏疾病(CKD)是一个全球性的公共卫生问题。它通常与贫血有关,随着CKD的恶化,贫血的患病率逐渐增加。目的:探讨慢性肾病不同分期与贫血的关系。材料与方法:本横断面研究于2016年1月至12月在孟加拉国Mymensingh医学院生理学系进行,为期一年。本研究共纳入174名受试者,其中患者87名,健康者87名。根据纳入和排除标准将研究对象分为病例组和对照组。采用自动分析仪对所有研究对象血液中血红蛋白浓度进行测定。结果:男性和女性CKD患者血中血红蛋白浓度均下降,分别为9.55±1.13 gm/dl和9.11±0.95 gm/dl,差异有统计学意义(p<0.01)。CKD 1期贫血55%,2期61%,3期70%,4期75%,5期86%。结论:这项研究表明,贫血的患病率是常见的在所有阶段的CKD患者在Mymensingh,孟加拉国。它强调需要定期检查贫血的慢性肾病患者和早期转诊到肾脏科医生。中国生物医学工程学报,2022;12(04):218-221
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