M. Ardeleanu, S. Mihai, R. Vidu, E. Diaconu, I. Popescu
{"title":"Design of Microfluidic Device and Measurements of MPWM for Single Cell /Particle Manipulation","authors":"M. Ardeleanu, S. Mihai, R. Vidu, E. Diaconu, I. Popescu","doi":"10.2478/bsmm-2019-0006","DOIUrl":null,"url":null,"abstract":"Abstract A microfluidic device designated for measurement of fluidic flows with different viscosity, necessary within trapping/realising of cells/particles system has been developed. We use a new concept as Microfluidic Pulse Width Modulation (MPWM) for controlling transport of a single cell/particle. The image processing helped the nano-hydraulic volumes/flow rates measurement, through tracking inovative methods with the purpose to build a flow sensor. The device open an unique opportunitie for single cell study with applications in biomedical devices, tools for biochemistry or analytical systems.","PeriodicalId":30754,"journal":{"name":"Scientific Bulletin of Valahia University Materials and Mechanics","volume":"44 1","pages":"39 - 43"},"PeriodicalIF":0.0000,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scientific Bulletin of Valahia University Materials and Mechanics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2478/bsmm-2019-0006","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Abstract A microfluidic device designated for measurement of fluidic flows with different viscosity, necessary within trapping/realising of cells/particles system has been developed. We use a new concept as Microfluidic Pulse Width Modulation (MPWM) for controlling transport of a single cell/particle. The image processing helped the nano-hydraulic volumes/flow rates measurement, through tracking inovative methods with the purpose to build a flow sensor. The device open an unique opportunitie for single cell study with applications in biomedical devices, tools for biochemistry or analytical systems.