Past-futures in experimental care: breast cancer and HIV medicine

IF 1.3 4区医学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

New Genetics and Society Pub Date : 2021-01-06 DOI:10.1080/14636778.2020.1861542

S. Day, William Viney, Jane Bruton, H. Ward

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引用次数: 6

Abstract

Cambrosio et al. (2018. “Extending Experimentation: Oncology’s Fading Boundary Between Research and Care.” New Genetics and Society 37 (3): 207–226) argue that “experimental care” in contemporary oncology involves the rapid merging of patient research and care, and invite further study into developments across other health conditions. We present a 2018–2019 study of experimental breast cancer care in an urban clinical setting in the light of two other studies in the same hospital group: in the same cancer service (2013–14) and, prompted by these earlier findings, an interview study in HIV services (2014–15). We found that patients and staff anticipated better outcomes by treating sub-types of breast cancer but they also hoped for a better one-size-fits-all approach, akin to the antiretroviral treatments introduced for HIV and explored in our interview study. We conclude that the promise of targeted treatment for sub-types of disease – variously described as experimental care, personalised, precision, stratified and sub-group medicine – is accompanied by hopes for a single, standard, effective approach.

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实验护理的过去和未来:乳腺癌和艾滋病医学

Cambrosio et al.(2018)。“扩展实验:肿瘤学研究与护理之间逐渐消失的界限”《新遗传学与社会》37(3):207-226)认为，当代肿瘤学的“实验性护理”涉及病人研究和护理的快速融合，并邀请进一步研究其他健康状况的发展。根据同一医院组的另外两项研究:同一癌症服务(2013-14)，以及基于这些早期发现的艾滋病毒服务访谈研究(2014-15)，我们提出了2018-2019年在城市临床环境中实验性乳腺癌护理的研究。我们发现，患者和工作人员期望通过治疗乳腺癌亚型获得更好的结果，但他们也希望有一种更好的一刀切的方法，类似于我们在访谈研究中探索的针对艾滋病毒的抗逆转录病毒治疗。我们得出的结论是，针对亚型疾病的靶向治疗的前景——被不同地描述为实验性护理、个性化、精确、分层和亚组医学——伴随着对单一、标准、有效方法的希望。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

New Genetics and Society 生物-生物工程与应用微生物

CiteScore

4.30

自引率

16.70%

发文量

审稿时长

>12 weeks

期刊介绍： New Genetics and Society: Critical Studies of Contemporary Biosciences is a world-leading journal which: -Provides a focus for interdisciplinary and multi-disciplinary, leading-edge social science research on the new genetics and related biosciences; -Publishes theoretical and empirical contributions reflecting its multi-faceted development; -Provides an international platform for critical reflection and debate; -Is an invaluable research resource for the many related professions, including health, medicine and the law, wishing to keep abreast of fast changing developments in contemporary biosciences. New Genetics and Society publishes papers on the social aspects of the new genetics (widely defined), including gene editing, genomics, proteomics, epigenetics and systems biology; and the rapidly developing biosciences such as biomedical and reproductive therapies and technologies, xenotransplantation, stem cell research and neuroscience. Our focus is on developing a better understanding of the social, legal, ethical and policy aspects, including their local and global management and organisation.