Formulation and Pharmacological Evaluation of Herbal Gel Containing Curcuma longa

Abstract

The aim of the present study is to formulate and evaluate a polyherbal gel that contains Curcuma longa extract. The ethanolic extract of C. longa’s rhizome was used to create a gel formulation in different concentrations (1, 2, 3, and 4%). Topical anti-inflammatory activity of gel was also assessed. Gel was prepared using Carbopol® 940 (1% w/v), C. longa extract, ethanol, propylene glycol 400, methyl paraben, propyl paraben, ethylenediaminetetraacetic acid, tri-ethanolamine, and the necessary amount of distilled water. The prepared formulations were assessed for their physical qualities, pH, spreadability, and ability to irritate skin to detect toxicity or side effects. The findings suggested that gel compositions were good in terms of appearance and uniformity.