Autologous blood injection for marked overfiltration early after trabeculectomy with mitomycin C.

K. Okada, H. Tsukamoto, M. Masumoto, K. Jian, M. Okada, H. Mochizuki, H. Mishima
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引用次数: 12

Abstract

PURPOSE After trabeculectomy with mitomycin C, extremely low intraocular pressure (IOP) with excess filtration may cause hypotonous maculopathy in the early postoperative period. We evaluated the effect of injecting autologous blood on reversing early postoperative marked hypotony after trabeculectomy with mitomycin C. METHODS Trabeculectomy with mitomycin C was performed in 258 eyes between 1994 and 1998. Peribleb autologous blood injection was performed in five eyes in which pressure patches were ineffective in reversing excess filtration. Approximately 0.1 to 0.3 ml of whole unclotted blood was slowly injected at least 3 mm from the edge of the flap using a sterile 27-gauge needle. RESULTS None of these eyes developed hypotonous maculopathy after injection. After a mean 31-month follow-up, all eyes had well-controlled IOP and visual acuity in three eyes was much improved. Postoperative complications included mild IOP elevation in one eye treated with laser suturelysis, and fibrinous pupillary membrane in one eye. CONCLUSION In the early postoperative period, autologous blood injection is effective in reversing excess filtration.
自体血液注射治疗丝裂霉素C小梁切除术后早期明显过滤。
目的丝裂霉素C小梁切除术后,极低的眼压(IOP)伴过度滤过可引起术后早期低张力黄斑病变。方法1994 ~ 1998年对258只眼行丝裂霉素C小梁切除术。5眼行外泡自体血液注射,压贴对过度滤过的逆转无效。用27号无菌针从皮瓣边缘至少3mm处缓慢注射约0.1至0.3 ml未凝固的全血。结果注射后无一例发生黄斑低张力病变。在平均31个月的随访后,所有眼睛的IOP控制良好,其中三只眼睛的视力明显改善。术后并发症包括单眼轻度IOP升高及单眼纤维性瞳孔膜。结论术后早期自体注血可有效逆转过度滤过。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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