Em busca das origens desenvolvimentais dos transtornos mentais

G. Polanczyk
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引用次数: 7

Abstract

INTRODUCTION: Developmental psychopathology is a discipline that integrates epidemiological, social, genetic, developmental, and psychopathological perspectives to understand the origins and courses of mental disorders. In the present paper, theoretical concepts and approaches applied with the purpose of understanding the developmental origins of mental disorders are discussed. RESULTS: According to developmental psychopathology, mental disorders are possible outcomes of the developmental process that depend upon social, genetic, and environmental influences. These factors are linked in different ways and levels, exerting a dimensional effect. The following factors are addressed: a) approaches to determine a causal effect between environmental factors and mental disorders; b) the importance of understanding biological mechanisms by which environmental and genetic factors exert their effect; c) genetic factors predicting the exposure to environmental stressors; d) genetic factors moderating the effect of environmental stressors. CONCLUSIONS: The origins of mental disorders can be clarified by data from studies that use complementary approaches and concepts, integrating social, genetic, environmental and developmental influences.
寻找精神障碍的发展起源
发展精神病理学是一门整合流行病学、社会、遗传、发展和精神病理学观点的学科,旨在了解精神障碍的起源和过程。在本文中,理论概念和方法的应用,以了解精神障碍的发展起源的目的进行了讨论。结果:根据发展精神病理学,精神障碍是依赖于社会、遗传和环境影响的发展过程的可能结果。这些因素以不同的方式和层次联系在一起,产生了维度效应。涉及以下因素:a)确定环境因素与精神障碍之间因果关系的方法;B)了解环境和遗传因素发挥作用的生物学机制的重要性;C)预测环境应激因素暴露的遗传因素;D)遗传因素缓和环境压力因素的影响。结论:精神障碍的起源可以通过使用互补方法和概念的研究数据来澄清,这些研究综合了社会、遗传、环境和发育影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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审稿时长
16 weeks
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