Immune Response towards COVID-19

Muhammad Akram, Waqas Ahmed, Abolfazl Jafari-Sales, NilgünKu, çulu, Mounir Bekhit, Prakash Ramakrishnan, El Hadji, S. Mbaye, F. Khan, O. Kilic, M. Amjad, Chishti, A. Sharif, M. Muddasar, Saeed, W. Elkhateeb, G. Daba
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Abstract

Background: As the world witnessed the outbreak of coronavirus illness 2019 (COVID-19), a disorder developed as a result of a novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), increasing genetics with healthcare evidence suggest a corresponding leadership to SARS as well as the Middle East Respiratory Syndrome (MERS). Aim: The aim of this review is to highlight Immune response of human body toward COVID-19. Materials and methods: This was a narrative review. A comprehensive literature search was done using PubMed, Google Scholar, Scopus, and EMBASE using the keywords, Immune Response; COVID-19; Vaccination; SARS-Cov-2; ACE2; Coronavirus; MERS. Results: A flow of viral components passes to the body by means of nostrils, mouth and eyes. SARS-CoV-2 is in a position to continue to become unnoticed extended than numerous influenza or coronaviruses. Its proteins can accomplish entry by unlocking the Angiotensin-Converting Enzyme 2 (ACE2) protein in the lung cells; viruses also possess antigens furthermore recognize that these are what cries the immunity into movement via making antibodies. Investigators demonstrate an extensive variety of immune cells respond to COVID-19 along with valuable source retrieval, discovering that might want to notify the manufacturing of a viable vaccination. Conclusion: The body's natural response to a viral infection is a non-invasive intrinsic response in which macrophages, neutrophils, and dendritic cells limit the virus's progression and may even prevent it by multiplying symptoms. This non-invasive solution is accompanied by an elastic response in which the body produces radicals that primarily adjust to the herpes virus.
对COVID-19的免疫反应
背景:随着2019冠状病毒病(COVID-19)的爆发,一种由新型冠状病毒严重急性呼吸综合征冠状病毒2 (SARS- cov -2)引起的疾病,越来越多的遗传学和医疗保健证据表明,SARS和中东呼吸综合征(MERS)相应的领导。目的:综述人体对COVID-19的免疫反应。材料与方法:本研究为叙述性综述。使用PubMed、Google Scholar、Scopus和EMBASE进行全面的文献检索,关键词为:免疫反应;COVID-19;疫苗接种;SARS-Cov-2;ACE2;冠状病毒;即。结果:病毒成分通过鼻孔、嘴巴和眼睛进入人体。SARS-CoV-2比许多流感或冠状病毒更容易继续被忽视。其蛋白可以通过解锁肺细胞中的血管紧张素转换酶2 (ACE2)蛋白来完成进入;病毒也拥有抗原,进一步认识到这些抗原是通过产生抗体来促使免疫活动的。研究人员展示了多种免疫细胞对COVID-19的反应以及有价值的来源检索,发现可能需要通知生产可行的疫苗。结论:人体对病毒感染的自然反应是一种非侵入性的内在反应,其中巨噬细胞、中性粒细胞和树突状细胞限制病毒的进展,甚至可能通过增加症状来预防病毒。这种非侵入性的解决方案伴随着一种弹性反应,在这种反应中,身体产生主要针对疱疹病毒的自由基。
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