BIOAVAILABILITY AND HEALTH RISK OF METALS IN URBAN DUSTS

I. Shabanda
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Abstract

Heavy metals gets into human body mostly through oral ingestion of environmental samples. To quantify the risks associated with oral ingestion of urban dust particularly by children, bioavalability fraction is required, as the total metal content may not give the real risk involved. Lead (Pb), Arsenic (As) and Cadmium (Cd) were analysed for bioavailable fraction in urban dust of this study. The risks of these metals on ingestion of urban dust by children were estimated. The results showed that metals solubilized in the gastrointestinal tract. This could possibly be due to metal distribution in the dust sample and the solubilisation of these metals in the gastrointestinal tract. The carcinogenic and non-carcinogenic risks results expressed that all the values were within the permissible limits of 1×10-6 1×10-4 with the order As > Cd > Pb. This indicates that children who ingested dust could have no possibility of both carcinogenic and non-cancer risks because both the CR, TCR and HQ and HI values were below the tolerable limits. Keywords: Bioavailability; risks; metals; urban dust
城市粉尘中金属的生物利用度和健康风险
重金属进入人体主要是通过环境样本的口服摄入。为了量化与口服城市粉尘(尤其是儿童)摄入相关的风险,需要生物利用度分数,因为总金属含量可能无法给出所涉及的实际风险。分析了城市粉尘中铅(Pb)、砷(As)和镉(Cd)的生物可利用性。这些金属对儿童摄入城市尘埃的风险进行了估计。结果表明,金属在胃肠道中溶解。这可能是由于粉尘样品中的金属分布以及这些金属在胃肠道中的溶解作用。致癌和非致癌风险结果均在1Ã-10-6 1Ã-10-4允许范围内,顺序为As > Cd > Pb。这表明,摄入粉尘的儿童不可能有致癌和非癌症风险,因为CR、TCR和HQ、HI值均低于可容忍限值。关键词:生物利用度;风险;金属;城市灰尘
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