IT11. Physical and biological aplications using self-asembled DNA nanostructures

Abstract

Nanobiotechnology has evolved into a unique interdisciplinary field involving physics, materials science, chemistry, biology, computer science, and multiple enginering fields. Likewise, DNA nanotechnology is a quickly developing field with esentialy no overwhelming technical dificultiesinhibitngprogres toward designing and fabricating new shapes of DNA nanostructures in al dimensions. In this field, researchers create artificial DNA sequences to self-asemble into target molecular nanostructures. The welunderstod Watson-Crick base-pairing rules are used to encode asembly instructions directly into the DNA molecules which provide basic building blocks for constructing functionalized nanostructures with two major features: self-asembly and self-align. In this talk, we present on self-asembled various DNA nanostructures. 1D and 2D periodicalypaterned nanostructures utilzing several distinct DNA motifs such as cros tiles, double crosover tiles as wel as single-stranded tiles wil be discused with unique design schemes and characteristics. We also discus new development of DNA fabrication methods such as Angle Control Scheme, Surface Asisted Growth and Dry & Wet Method. At he end of the talk, we adresaplications of DNA nanotechnology which wil show feasibilty to construct various physical devices and biological/chemical sensors with DNA nanostructures[1,2].