Micronucleus assay in epithelial cells from the oral cavity and urinary tract in female smokers and non-smokers

E. Błaszczyk, Danuta Mielżyńska-Švach
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引用次数: 7

Abstract

pooled analysis of the frequency of binucleated cells and condensed chromatin cells in 18 studied women, statistically significant differences were noted only in epithelial cells from the oral cavity in comparison to those of the urinary tract. Non-pooled results demonstrated no differences in cytogenetic damage frequency in cells collected from the oral cavity and isolated from the urine. The lack of differences in the observed frequencies of micronuclei in buccal and urothelial cells could be an effect of the small size of the sampled group, smoking pattern of the women and the number of cigarettes smoked per day. Micronucleus assay in epithelial cells from the oral cavity
女性吸烟者和非吸烟者口腔和尿道上皮细胞的微核测定
对18名被研究女性的双核细胞和浓缩染色质细胞的频率进行汇总分析,发现只有口腔上皮细胞与尿道上皮细胞有统计学上的显著差异。非合并结果表明,从口腔收集的细胞和从尿液中分离的细胞在细胞遗传学损伤频率上没有差异。在口腔和尿路上皮细胞中观察到的微核频率没有差异,这可能是采样组规模小、女性吸烟模式和每天吸烟数量的影响。口腔上皮细胞的微核测定
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