Micronucleus assay in epithelial cells from the oral cavity and urinary tract in female smokers and non-smokers

Abstract

pooled analysis of the frequency of binucleated cells and condensed chromatin cells in 18 studied women, statistically significant differences were noted only in epithelial cells from the oral cavity in comparison to those of the urinary tract. Non-pooled results demonstrated no differences in cytogenetic damage frequency in cells collected from the oral cavity and isolated from the urine. The lack of differences in the observed frequencies of micronuclei in buccal and urothelial cells could be an effect of the small size of the sampled group, smoking pattern of the women and the number of cigarettes smoked per day. Micronucleus assay in epithelial cells from the oral cavity