Strategies and Challenges to Develop Therapeutic Candidates against COVID-19 Pandemic

Abstract

Although there is continuous work in progress in some of the above mentioned approaches, but there is still no drug/vaccine available to treat COVID-19 Drug repurposing offers an economical and rapid strategy to discover a potential therapeutic agent in the current hectic situation This compilation may be helpful to the researchers, drug developers and health agencies to look into the matter and work against the possible targets to develop a therapeutic candidate against COVID-19 The challenge associated with drug repurposing is the inadequate efficacy of single therapeutic candidate Another complication associated with this approach is to search and analyze the huge amount of previously reported data to make efficient and effective use against a new indication The complex/unclear events of the pathophysiology of SARS-CoV-2 also offer a great challenge to select a candidate for repurposing