Vibrational circular dichroism in the near infrared: instrumental developments and applications.

Abstract

Near infrared vibrational circular dichroism spectra in the region of 1300 to 800 nm were recorded for 12 enantiomeric pairs of molecules with a home-made dispersive apparatus. With respect to earlier measurements, a better signal-to-noise ratio was obtained, thus allowing a more precise determination of molecular parameters. A detailed examination of the spectra between 1300 and 1100 nm allowed us to correlate the data of the different molecules, based on local properties of given molecular moieties. The relevance of this correlation in configurational and/or conformational studies is discussed.