Comparison of the Effectiveness of Leaf Extracts of Anredera cordifolia, Psidium guajava and Pogostemon cablin on Inhibitory Power Over Escherichia coli Bacteria

Q3 Pharmacology, Toxicology and Pharmaceutics

Vitae Pub Date : 2021-10-04 DOI:10.17533/udea.vitae.v28n3a345386

Budianto Budianto, Alif Gita Arum sari, N. Inayah, F. Fatmaningrum, A. Suparmi

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引用次数: 1

Abstract

Background: the current research studies why it is effective using Anredera cordifolia, Psidium guajava, and Pogostemon cablin by the local community as a traditional medicine for diarrhea treatment caused by Escherichia colibacteria. Objectives: We compared the inhibitor effectiveness of three leaf extracts against Escherichia coli; we also identified the anti-bacterial substances contained in leaf extracts. Methods: We determined the bacterial test activity using the "agar diffusion" method and the thin layer chromatography (TLC) as qualitative analysis for determining the anti-bacterial substances contained in the extract. Results: The Pogostemon cablin leaf extract contained terpenoids, phenolic, and flavonoids compound as bacterial inhibitors, and the comparison showed that Pogostemon cablin leaf extract had the greatest bacterial inhibition power. Conclusion: The antibiotic substances found in the leaf extracts of Anredera cordifolia, Psidium guajava, and Pogostemon cablin can be used as traditional medicine. The breakthrough was evidenced by the ability to inhibit Escherichia coli bacteria. This research shows that traditional medicine has ancient knowledge used by this paper

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菖蒲叶提取物、番石榴叶提取物和广藿香叶提取物对大肠杆菌抑制作用的比较

背景:目前研究的是为什么当地社区将鹿茸、番石榴和广藿香作为传统药物治疗大肠杆菌引起的腹泻有效。目的:比较三种叶提取物对大肠杆菌的抑制作用;我们还鉴定了叶提取物中含有的抗菌物质。方法:采用“琼脂扩散法”测定细菌试验活性，薄层色谱(TLC)定性分析测定提取物中抗菌物质。结果:广藿香叶提取物中含有萜类化合物、酚类化合物和黄酮类化合物，对细菌具有抑制作用，经比较发现，广藿香叶提取物对细菌的抑制作用最强。结论:菖蒲、番石榴和广藿香叶提取物中含有抗菌成分，可作为中药使用。这一突破是由抑制大肠杆菌的能力证明的。这一研究表明，传统医学具有本文所使用的古老知识

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来源期刊

Vitae PHARMACOLOGY & PHARMACY-

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The journal VITAE is the four-monthly official publication of the School of Pharmaceutical and Food Sciences, and its mission is the diffusion of the scientific and investigative knowledge in the various fields of pharmaceutical and food research, and their related industries. The Journal VITAE is an open-access journal that publishes original and unpublished manuscripts, which are selected by the Editorial Board and then peer-reviewed. The editorial pages express the opinion of the Faculty regarding the various topics of interest. The judgments, opinions, and points of view expressed in the published articles are the responsibility of their authors.