PET/CT imaging in the diagnosis and treatment planning in recurrent ovarian cancer

Q4 Medicine
Michał Leśniak, M. Stelmach, Michał Mleko, Joanna Spaczyńska, M. Duda-Wiewiórka, M. Kabzińska-Turek, T. Popiela, K. Pityński
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引用次数: 0

Abstract

follow-up period after primary treatment. No PET/CT was performed in the control group. Results: Microscopic recurrence of ovarian cancer in the region of pelvic lymph nodes was found in 29 out of 34 patients with SUV ≥2.4 and in 6 out of 51 patients with SUV <2.4. SUV ≥3.5 for para-aortic lymph nodes was associated with recurrence in this region in 24/25 cases. SUV <3.5 confirmed recurrence in only 1 out of 60 patients. Conclusions: PET/CT is characterized by high efficacy in detecting recurrence after primary treatment. PET/CT performed in the study group as part of monitoring patients after standard treatment of ovarian cancer was associated with longer survival after secondary treatment compared to women without PET/CT follow-up. SUV threshold for active neoplastic process was 3.5 for para-aortic location and 2.4 for pelvic lymph nodes.
PET/CT成像在复发性卵巢癌诊断及治疗方案中的应用
初次治疗后的随访期。对照组未行PET/CT检查。结果:SUV≥2.4的34例患者中29例盆腔淋巴结镜下复发,SUV <2.4的51例患者中6例盆腔淋巴结镜下复发。24/25的主动脉旁淋巴结SUV≥3.5与该区域复发相关。60例患者中只有1例SUV <3.5确诊复发。结论:PET/CT对原发性治疗后复发的检测具有较高的疗效。与未进行PET/CT随访的女性相比,研究组在卵巢癌标准治疗后进行PET/CT监测的患者在二次治疗后的生存期更长。主动脉旁病变的SUV阈值为3.5,盆腔淋巴结的SUV阈值为2.4。
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来源期刊
Current Gynecologic Oncology
Current Gynecologic Oncology Medicine-Obstetrics and Gynecology
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