Multiparametric Investigations on Solvation Behaviour and Spectral Shifts of Symmetric Aromatic Diselenides: A case study of Diphenyldiselenide

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-08-24 DOI:10.1080/00319104.2023.2248343

Shabnam Raheem, Richu, Tabee Jan, M. Mustafa, G. M. Peerzada, Ashwani Kumar, M. Rizvi

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引用次数: 0

Abstract

ABSTRACT Decorating symmetric aromatic diselenide motif such as in diphenyldiselenide (DPDSe) with diverse supra-functionalities provides a plethora of bioactivities for pharmacological applications. Solvent studies of bioactive molecules are vital descriptors for their drug development as these can predict the drug–target interaction. This study aims to evaluate the influence of intermolecular interactional forces on the solvation behaviour and spectral shifts of DPDSe. The solvation behaviour of DPDSe was evaluated primarily via solvent polarity and solvent parameters. The observed solvatochromic shifts were analysed with various solvent study models, of which Kamlet–Taft and Catalan models were found to be most suitable for describing intermolecular interactions of DPDSe. The experimental data suggest an overall red shift with increasing solvent polarity. Moreover, data analysis using solvatochromic models predict negative coefficients for solvent dipolarity (π*) and solvent polarisabilities (SP) and (SdP). The studied dipole moment values indicate the more polar nature of DPDSe in the excited state relative to the ground state, further corroborating the observed bathochromic shift with increasing solvent polarity.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.