FORMULASI KRIM EKSTRAK DAUN NANGKA (Artocarpus heterophyllus L.) TERHADAP BAKTERI Propionibacterium acne

Jurnal Penelitian Farmasi & Herbal Pub Date : 2020-04-30 DOI:10.36656/jpfh.v2i2.258

Fahma Shufyani, Sara Yudistira, Muhammad Mabrur, Armaliza Permata Sari

{"title":"FORMULASI KRIM EKSTRAK DAUN NANGKA (Artocarpus heterophyllus L.) TERHADAP BAKTERI Propionibacterium acne","authors":"Fahma Shufyani, Sara Yudistira, Muhammad Mabrur, Armaliza Permata Sari","doi":"10.36656/jpfh.v2i2.258","DOIUrl":null,"url":null,"abstract":"Jackfruit leaf is (Artocarpus heterophyllus L) is one of the natural ingredients that can be used as a therapeutic treatment of acne. To facilitate its use the extract is made in the form of a cream. This study aims to determine the antibacterial activity of anti-acne cream jackfruit leaf extract against propionibacterium acne with concentrations of 30%, 50%, 70%, and 90%. Compounds that act as antibacterials on jackfruit leaves include flavonoids, tannins, saponins. This research method is an ANOVA one way method. The extraction method used is the maceration method. The tests include physical stability test and anti-acne activity test. Physical preparation stability test is carried out every 6 days for 3 weeks. While the anti-acne activity observation test was carried out on Propionibacterium acne bacteria. Based on the observation of organoleptic preparations of formulations 1 and 2 there was no change, while 3,4,5 there was a change. Anti- acne activity test showed that formulations 1 and 2 were more effective than formulations 3, 4, 5 with an average inhibition zone of 9.5 mm.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"5 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jurnal Penelitian Farmasi & Herbal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36656/jpfh.v2i2.258","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 1

Abstract

Jackfruit leaf is (Artocarpus heterophyllus L) is one of the natural ingredients that can be used as a therapeutic treatment of acne. To facilitate its use the extract is made in the form of a cream. This study aims to determine the antibacterial activity of anti-acne cream jackfruit leaf extract against propionibacterium acne with concentrations of 30%, 50%, 70%, and 90%. Compounds that act as antibacterials on jackfruit leaves include flavonoids, tannins, saponins. This research method is an ANOVA one way method. The extraction method used is the maceration method. The tests include physical stability test and anti-acne activity test. Physical preparation stability test is carried out every 6 days for 3 weeks. While the anti-acne activity observation test was carried out on Propionibacterium acne bacteria. Based on the observation of organoleptic preparations of formulations 1 and 2 there was no change, while 3,4,5 there was a change. Anti- acne activity test showed that formulations 1 and 2 were more effective than formulations 3, 4, 5 with an average inhibition zone of 9.5 mm.

查看原文本刊更多论文

nnumg提取物配方(Artocarpus heolelus L)对丙戊酸细菌

菠萝蜜叶(Artocarpus heterophyllus L)是天然成分之一，可以用作治疗痤疮的治疗方法。为了方便使用，提取液被制成乳膏的形式。本研究旨在测定菠萝蜜叶提取物抗痘霜对浓度为30%、50%、70%、90%的痤疮丙酸杆菌的抑菌活性。菠萝蜜叶子上的抗菌化合物包括类黄酮、单宁、皂苷。本研究方法为单因素方差分析方法。所采用的提取方法为浸渍法。测试包括物理稳定性测试和抗痤疮活性测试。物理制剂稳定性试验每6天进行一次，持续3周。同时对痤疮丙酸杆菌进行抗痤疮活性观察试验。从感官制剂的观察来看，剂型1和2没有变化，而剂型3、4、5有变化。抗痘活性试验表明，配方1、2比配方3、4、5更有效，平均抑制面积为9.5 mm。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Jurnal Penelitian Farmasi & Herbal

自引率

0.00%

发文量