Case Study: Abnormal Presentation of Infective Endocarditis With Streptococcus Canis and Chiari Network

Shahbaz Afzal, Ryan F. Russell, A. Chekhov
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Abstract

Here we present a rare case of infective endocarditis (IE) with Streptococcus canis and Chiari network in an 85 year old female living with multiple dogs and open skin of lower extremity predisposing her to bacteremia. Underlying abnormalities of the cardiac chambers such as Chiari network predisposes to a higher incidence of bacterial seeding and causing IE. A Chiari network is usually asymptomatic and of no clinical significance but can worsen prognosis in IE. IE carries a significant morbidity and mortality burden and when diagnosed early can be a lifesaving diagnosis. Due to the wide range of complications, early diagnosis and treatment with targeted antimicrobial therapy and consideration of early surgical intervention are vital to the evaluation and treatment of IE. Though Staphylococci, Streptococci, Enterococci, HACEK organisms amount for the majority of IE, some atypical organisms including group G Streptococci such as S. canis have been reported to carry high mortality and hospitalization risk in patients with bacteremia. S. canis is a group G beta-hemolytic Streptococci which normally resides on the skin and mucosal surfaces of dogs. This Case Report shines light on the versatility of microorganisms that can cause IE in a patient with underling Chiari network, and the risk of morbidity and mortality with such species highlighting the importance of early diagnosis and treatment.
个案研究:传染性心内膜炎的异常表现与犬链球菌和基亚瑞网络
在此,我们报告一例罕见的感染心内膜炎(IE)与犬链球菌和Chiari网络在85岁的女性生活与多只狗和开放的下肢皮肤,使她易患菌血症。心脏腔的潜在异常,如Chiari网络,易导致细菌播种和IE的高发生率。Chiari网络通常无症状,无临床意义,但可恶化IE的预后。IE具有显著的发病率和死亡率负担,早期诊断可能是挽救生命的诊断。由于并发症广泛,早期诊断和靶向抗菌药物治疗以及考虑早期手术干预对IE的评估和治疗至关重要。虽然大多数IE是由葡萄球菌、链球菌、肠球菌、HACEK菌组成,但一些非典型菌,包括G群链球菌,如S. canis,在菌血症患者中具有很高的死亡率和住院风险。犬链球菌是一种G群溶血性链球菌,通常存在于狗的皮肤和粘膜表面。本病例报告揭示了可在具有底层Chiari网络的患者中引起IE的微生物的多样性,以及这些物种的发病率和死亡率风险,强调了早期诊断和治疗的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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